1. Discovery of RNA-guided DNA integration by CRISPR-associated transposases Klompe, Sanne Eveline 2023 Theses Molecular biologyDNA-protein interactionsRNA-protein interactionsBacterial genomesImmunologyProkaryotesEscherichia coli
2. Epigenetic targeting of metabolic and lineage abnormality in cancer Karagiannis, Dimitrios 2023 Theses ChromatinMolecular biologyGeneticsEpigeneticsGene expressionCancer--TreatmentLungs--CancerEsophagus--CancerCell metabolism--Regulation
3. Evolutionary rate determinants and functional optimization of proteins Usmanova, Dinara R. 2023 Theses Evolution (Biology)Molecular biologyGeneticsProteins
4. Identifying Critical Regulatory Elements of Alternative Splicing Recinos, Yocelyn 2023 Theses BiologyMolecular biologyGenetic engineeringRNA splicingExons (Genetics)Mammals--Genetics
5. Investigating the determinants of resistance to quinine and chloroquine using a novel Plasmodium falciparum genetic cross Kanai, Mariko 2023 Theses MicrobiologyGeneticsMolecular biologyPlasmodium falciparumQuinine--Therapeutic useMalaria--TreatmentDrug resistance
6. NMR Studies of the GCN4 Transcription Factor and Hox DNA Consensus Sequences Crawley, Timothy 2023 Theses BiophysicsMolecular biologyDNABootstrap (Statistics)Nuclear magnetic resonance spectroscopyDNA-binding proteins
7. Non-canonical WDR33 Isoforms: Characterization, Regulation, and Functional Significances in STING-Mediated Innate Immune Responses Liu, Lizhi 2023 Theses Molecular biologyImmunologyBiochemistryAmino acid sequenceGene expressionMessenger RNAOligomerizationInterferon
8. Rie1 and Sgn1 form an RNA-binding complex that enforces the meiotic entry cell fate decision Gaspary, Alec 2023 Theses BiologyCytologyMolecular biologyYeast--GeneticsSaccharomyces cerevisiae--Genetic aspectsRNA-protein interactionsMeiosis
9. SPIDR: The development and application of a highly multiplexed CLIP-seq method Wolin, Erica 2023 Theses Molecular biologyRNA-protein interactionsRNA--Analysis
10. The role of ER-mitochondria contact sites in the regulation of glucose metabolism: a tale of two mitochondria and its relevance to amyotrophic lateral sclerosis Tamucci, Kirstin Arianna 2023 Theses BiochemistryMolecular biologyNutritionGlucose--MetabolismMitochondriaMitochondrial membranesEndoplasmic reticulumMotor neuronsAmyotrophic lateral sclerosis
11. Understanding the molecular, cellular, and circuit defects characterizing the early stages of Alzheimer’s disease Virga, Daniel Michael 2023 Theses NeurosciencesAlzheimer's disease--PathophysiologyAlzheimer's disease--EtiologyCytologyMolecular biologyNervous system--DiseasesHippocampus (Brain)SynapsesDendritesMitochondrial pathology
12. Analysis of Conformational Continuum and Free-energy Landscapes from Manifold Embedding of Single-particle Cryo-EM Ensembles of Biomolecules Seitz, Evan Elliott 2022 Theses Molecular biologyBiomoleculesElectron microscopy—Data processingMachine learningRiemannian manifoldsGibbs' free energyPath analysis (Statistics)RibosomesCOVID-19 (Disease)--Data processing
13. A non-canonical Hippo signaling pathway regulates DeltaNp63 in cancer cells Low Calle, Ana Maria 2022 Theses Molecular biologySquamous cell carcinomaTranscription factors
14. Bacterial Genome Engineering with CRISPR RNA-Guided Transposons Vo, Phuc Hong 2022 Theses Molecular biologyMicrobiologyBacterial geneticsBacterial genomesTherapeuticsEscherichia coli--GeneticsTransposonsDNACRISPR (Genetics)
15. Characterization of pathogenic BicD2 mutations in vitro and in vivo. Yi, Julie Young Joo 2022 Theses CytologyMolecular biologyNeurosciencesMicrotubulesEukaryotic cellsDyneinMutagenesisKinesin
16. Developing and applying novel imaging methods for human diseases Bekdash, Ramsey Azeez 2022 Theses Molecular biologyBiologyFluorescence microscopyElectrophysiologyDiagnostic imagingCOVID-19 (Disease)--TreatmentMetabolism
17. Noncoding translation mitigation Kesner, Jordan 2022 Theses Biology--ClassificationMolecular biologyCytologyEukaryotic cells--GeneticsAmino acid sequenceGenomesNucleotide sequenceRNA
18. Nucleolar transcription and its connections to nucleolar homeostasis and mitochondrial stress responses Feng, Shuang 2022 Theses Molecular biologyNucleic acidsHomeostasisMitochondriaCarcinogenesisNervous system--Diseases
19. Regulation of synapse density by Pumilio RNA-binding proteins Randolph, Lisa Kathryn 2022 Theses NeurosciencesCytologyMolecular biologyNeuronsSynapsesRNA-protein interactions
20. Single-cell Analysis of Alopecia Areata Lee, Yoo Jin 2022 Theses ImmunologyMolecular biologyAlopecia areata--Animal modelsMiceBaldnessPathologyCytokinesLymphocytesNucleotide sequenceCancer--Treatment
21. The Role of Chromatin in Olfaction Kodra, Albana Lavinia 2022 Theses ChromatinOlfactory receptor genesCOVID-19 (Disease)--Psychological aspectsGeneticsMolecular biologyBiochemistryEpithelium
22. The role of microRNA-219 in Alzheimer’s Disease-related tau proteostasis and pathology Cho, Joshua 2022 Theses Molecular biologyAlzheimer's disease--PathophysiologyNervous system--DiseasesDrosophila melanogasterMicePhosphorylation
23. The role of PPARgamma acetylation and Adipsin in adipose tissue dysfunction Aaron, Nicole 2022 Theses PharmacologyMolecular biologyMedicineAdipose tissuesHomeostasisAcetylationMacrophages
24. A p53-independent role for MDM2-MDMX in cell cycle progression Klein, Alyssa Michelle 2021 Theses CytologyMolecular biologyBiochemistryCancerMutation
25. Discovery of Novel Ferroptosis Regulators Using Genetic and Lipidomic Analyses Bezjian, Carla Tara 2021 Theses CytologyMolecular biologyBiochemistryCell deathGenetic regulationPhospholipids
26. Epitranscriptomic Alterations in Alzheimer’s Disease: The Role of MicroRNA Methylation in the Regulation of Tau Proteostasis Kim, Yoon Anna 2021 Theses NeurosciencesPathologyMolecular biologyAlzheimer's disease--Genetic aspectsMicroRNAMethyltransferasesNervous system--DegenerationPhosphorylationDrosophila--GeneticsRats--GeneticsMice--Genetics
27. Function and Regulation of ALS/FTD-associated RNA Binding Protein FUS Tsai, Yueh-Lin 2021 Theses BiologyCytologyMolecular biologyRNA-protein interactionsAmyotrophic lateral sclerosisDementia
28. Leveraging the potential of human iPSC-derived cardiomyocytes: From modeling congenital heart disease to treating myocardial infarction Liu, Bohao 2021 Theses Biomedical engineeringMolecular biologyMedicineMyocardial infarctionCongenital heart diseaseHeart cellsStem cellsHuman beings
29. Mutagenic Repair Outcomes of DNA Double-Strand Breaks Al-Zain, Amr M. 2021 Theses BiologyMolecular biologyDouble-stranded RNACancer--EtiologyCancer--Genetic aspectsGenomesMutagenesis
30. Neurometabolic alterations after traumatic brain injury: Links to mitochondria-associated ER membranes and Alzheimer’s disease Agrawal, Rishi Raj 2021 Theses Molecular biologyCytologyNeurosciencesBrain--Wounds and injuriesAlzheimer's disease--EtiologyMitochondrial membranes
31. Non-apoptotic Caspase-8 Signaling Mediates Retinal Angiogenesis Johnson, Kendra Vincia 2021 Theses NeurosciencesCytologyMolecular biologyRetina--DiseasesRetina--Blood-vesselsNeovascularizationRetinal degeneration--Animal models
32. Phenotypic dissection and therapeutic manipulation of cell differentiation programs in the salivary gland epithelium and human Adenoid Cystic Carcinomas Viragova, Sara 2021 Theses CytologyMolecular biologySalivary glandsEpithelium--DiseasesAdenoid cystic carcinomaCancer--Radiotherapy
33. Pparg Drives Luminal Differentiation and Luminal Tumor Formation in the Urothelium Tate, Tiffany 2021 Theses OncologyCytologyMolecular biologyUrinary organsBladder--CancerBasal cell carcinoma
34. Spatially determined olfactory receptor choice is regulated by Nfi-dependent heterochromatin silencing and genomic compartmentalization Bashkirova, Elizaveta Vladimirovna 2021 Theses Molecular biologyHeterochromatinOlfactory receptorsOlfactory receptor genes
35. Stress and Rab35 modulate Alzheimer’s disease-related protein trafficking Zhuravleva, Viktoriya 2021 Theses NeurosciencesBiologyMolecular biologyAlzheimer's disease--ResearchStress (Physiology)Glucocorticoids
36. Structure and Function of a Transposon-Encoded CRISPR-Cas System Halpin-Healy, Tyler Sheehan 2021 Theses BiochemistryBiophysicsMolecular biologyVibrio choleraeRNADNA
37. The role of RNA base modification m⁶A in RNA turnover and genome dynamics in B cell programmed DNA recombination Nair, Lekha 2021 Theses ImmunologyMolecular biologyRNADNAMethyltransferasesMethylationGene rearrangement
38. Atf5 Links Olfactory Receptor Induced Stress Response to Proper Neuronal Function Kahiapo, Jerome Keoki 2020 Theses CytologyBiochemistryMolecular biologyOlfactory receptor genesSmellSensory neuronsMammals
39. Evolutionary and Functional Diversity of Regulatory Factors and Sequences that Coordinate Gene Expression Park, Jimin 2020 Theses Biology--ClassificationMolecular biologyMicrobiologyGenetic regulationGene expressionDNA--Synthesis
40. Generative Models for Synthetic Biology Blazejewski, Tomasz 2020 Theses BioinformaticsBiology--ClassificationMolecular biologySynthetic biologyMachine learningAmino acid sequence
41. Leveraging DNA Damage Response Pathways to Enhance the Precision of CRISPR-Mediated Genome Editing Nambiar, Tarun S. 2020 Theses GeneticsMolecular biologyGene editingGenomesDNA
42. Neuronal Topography in a Cortical Circuit for Innate Odor Valence Costantini, Daniel 2020 Theses NeurosciencesMolecular biologyOlfactory receptorsOdorsMiceNeurons
43. Proximal-distal patterning of the lung: molecular determinants in lung development and evolution van Soldt, Benjamin Jonathan 2020 Theses Developmental biologyGeneticsMolecular biologyLungsPulmonary alveoliMammals--Development
44. RNA mediated mechanisms of motor neuron death and dysfunction in SMA Van Alstyne, Meaghan 2020 Theses CytologyMolecular biologySpinal muscular atrophyMotor neuronsRNA
45. The autophagosomal perspective: Tissue-specificity and cell-specificity of the autophagic response to starvation in vivo Yang, Young Joo 2020 Theses Molecular biologyBioinformaticsVeterinary medicineAutophagic vacuoles
46. The contribution of bone to the physiology of danger Berger, Julian Meyer 2020 Theses EndocrinologyNeurosciencesMolecular biologyBonesDanger perception--ResearchMiceRatsHuman beings
47. The FYN-TRAF3IP2 gene fusion drives oncogenic NF-κB signaling in peripheral T cell lymphoma Kim, Christine Sheila 2020 Theses Molecular biologyGeneticsOncologyHTLV (Viruses)CarcinogenesisGene fusion
48. The Role of N6-methyladenosine RNA Methylation in the Regulation of Hematopoietic Stem Cells Lee, Heather 2020 Theses CytologyMolecular biologyHematopoietic stem cellsDNA--MethylationCell differentiation
49. The role of SMARCAD1 during replication stress Joseph, Sarah 2020 Theses Molecular biologyGeneticsBreast--Cancer--Genetic aspectsOvaries--Cancer--Genetic aspectsHeterozygosity
50. Understanding the Evolution of Recombination Rate Variation and PRDM9 Baker, Zachary 2020 Theses Biology--ClassificationEvolution (Biology)Molecular biologyMeiosisGenetic recombination