Language: English / Subject: Biochemistry and Biophysics | Search Results

1. Directed Evolution of Protein Receptor Binding for Small Molecule Therapeutics Using Fluorescence Polarization

: Bannier, Sean David
: 2021
: Theses
: ChemistryBiochemistryBiophysicsTetracylcinesProtein bindingPolarization (Light)Yeast

2. How to steal ribosomes: structural studies of two different internal ribosome entry sites

: Neupane, Ritam
: 2021
: Theses
: BiochemistryBiophysicsVirologyRibosomesEukaryotic cellsCrickets

3. Structural and Biochemical Studies of the Human pre-mRNA 3’-end Processing Complex

: Hamilton, Keith
: 2021
: Theses
: BiochemistryBiophysicsMessenger RNA--AnalysisMutagenesis

4. Investigation of Ribonuclease HI handle region dynamics using Solution-state nuclear magnetic resonance spectroscopy, Molecular Dynamic simulations and X-ray crystallography

: Martin, James Arthur
: 2020
: Theses
: BiophysicsBiochemistryHIV (Viruses)Mouse leukemia virusesRNAEndonucleasesNuclear magnetic resonance spectroscopy

5. Structural and Biophysical Studies of Hair Cell Mechanotransduction Proteins

: Dionne, Gilman
: 2020
: Theses
: BiochemistryBiophysicsProteinsCellular signal transduction--Research

6. The Critical Assessment of Protein Dynamics using Molecular Dynamics (MD) Simulations and Nuclear Magnetic Resonance (NMR) Spectroscopy Experimentation

: Hsu, Andrew
: 2020
: Theses
: BiophysicsBiochemistryNuclear magnetic resonance spectroscopyMolecular dynamics--Computer simulation

7. Biomolecular NMR spectroscopy: Application to the study of the piRNA-pathway protein GTSF1, and backbone and side-chain spin relaxation methods development

: O'Brien, Paul
: 2019
: Theses
: BiophysicsBiochemistryNuclear magnetic resonance spectroscopyProteins--StructureMolecular dynamics

8. Nucleosome Curtains and their application to the study of DNA condensation by condensin

: Moevus, Corentin Jean
: 2019
: Theses
: BiochemistryBiophysicsDNACondensed matter

9. Solving Challenging Structures using Single-Particle Cryogenic Electron Microscopy

: Tan, Yong Zi
: 2019
: Theses
: BiochemistryBiophysicsElectron microscopyMacromolecules--StructureRibosomesMembrane proteinsCytology--Technique

10. Using single molecule magnetic tweezers to dissect titin energy release during muscle contraction

: Eckels, Edward Charles
: 2019
: Theses
: BiophysicsBiochemistryPhysiologyMagnetic tweezersMuscle contractionProtein folding

11. Allosteric Coupling, Nucleotide Binding and ATP Hydrolysis by Hsp70 Chaperones on a Structural Basis

: Wang, Wei
: 2018
: Theses
: BiologyBiochemistryBiophysicsAllosteric regulationHeat shock proteins

12. Dynamic Nuclear Polarization with Biradical Affinity Reagents

: Rogawski, Rivkah
: 2018
: Theses
: BiophysicsChemistryBiochemistryPolarization (Nuclear physics)Biradicals

13. Integration of EGFR and LIN-12/Notch signaling in Vulval Precursor Cell fate specification in Caenorhabditis elegans

: Underwood, Ryan
: 2018
: Theses
: BiochemistryMetazoaCell interactionCellular signal transductionBiophysics

14. RNA force field with accuracy comparable to state-of-the-art protein force fields

: Tan, Dazhi; Piana, Stefano; Dirks, Robert M.; Shaw, David Elliot
: 2018
: Articles
: BiochemistryBiophysicsRNA-protein interactionsMolecular dynamicsNucleic acids

15. Routine single particle CryoEM sample and grid characterization by tomography

: Noble, Alex J.; Dandey, Venkata P.; Wei, Hui; Brasch, Julia; Chase, Jillian; Acharya, Priyamvada; Tan, Yong Zi; Zhang, Zhening; Kim, Laura Y.; Scapin, Giovanna; Rapp, Micah Allen; Eng, Edward T.; Rice, William J.; Cheng, Anchi; Negro, Carl J.; Shapiro, Lawrence S.; Kwong, Peter D.; Jeruzalmi, David; des Georges, Amedee; Potter, Clinton; Carragher, Bridget
: 2018
: Articles
: TomographyBiochemistryParticlesBiophysicsElectron microscopy

16. Structural and biophysical studies of the Drosophila melanogaster Dpr and DIP families

: Cosmanescu, Filip
: 2018
: Theses
: BiochemistryNeurosciencesBiophysicsDrosophila melanogasterNeurons

17. Systematically Mapping the Epigenetic Context Dependence of Transcription Factor Binding

: Kribelbauer, Judith Franziska
: 2018
: Theses
: BiochemistryBioinformaticsBiophysicsTranscription factorsGene regulatory networksEpigenetics

18. The Role of Eukaryotic Recombinase Loop L1 During Homologous Recombination

: Steinfeld, Justin Benjamin
: 2018
: Theses
: BiophysicsBiochemistryGeneticsGenetic recombinationEukaryotic cells

19. The Saccharomyces cerevisiae Srs2 Helicase Regulates Homologous Recombination through the Disassembly of Recombination Intermediates

: Kaniecki, Kyle Stephen
: 2018
: Theses
: GeneticsBiophysicsBiochemistrySaccharomyces cerevisiaeGenetic recombination

20. Cryo-electron microscopy and single particle reconstructions of the Leishmania major ribosome and of the encephalomyocarditis virus internal ribosome entry site bound to the 40S subunit

: Jobe, Amy Beth
: 2017
: Theses
: Electron microscopyRibosomesLeishmaniaRNACryoelectronicsBiologyBiochemistryBiophysics

21. Nanoscale Electrical and Coarse-grained Molecular Dynamics Studies of Influenza Hemagglutinin-mediated Membrane Fusion Pores

: Alcott, Brett Eugene
: 2017
: Theses
: BiophysicsBiochemistryVirologyMolecular dynamicsMembrane fusion

22. Regulation of Release Factor 2 in Non-canonical Translation Pathways

: Huang, Bridget Yih Jiin
: 2017
: Theses
: Bacterial proteinsRibosomesBiochemistryProteins--SynthesisBiophysics

23. Single-molecule observations of hRPA, RAD51, and RAD52 on single-stranded DNA

: Ma, Chu Jian
: 2017
: Theses
: BiochemistryBiophysicsDNA replicationGenetic recombinationMolecular biology

24. Structural and Functional Studies of TRPML1 and TRPP2

: Benvin, Nicole Marie
: 2017
: Theses
: BiologyBiochemistryBiophysicsTRP channelsProteins--Structure

25. Cryo-electron microscopy studies of dynamical features of ribosomes during the translation process

: Sun, Ming
: 2016
: Theses
: BiophysicsProteins--StructureRibosomes--StructureRibosomesCryoelectronicsBiologyBiochemistry

26. Oxidative Folding in Bacteria: Studies Using Single Molecule Force Spectroscopy

: Kahn, Thomas
: 2016
: Theses
: Protein foldingOxidoreductasesEscherichia coli--PhysiologyOxidationBiophysicsBiochemistry

27. Understanding complex biomolecular systems through the synergy of molecular dynamics simulations, NMR spectroscopy and X-Ray crystallography

: Zeiske, Tim
: 2016
: Theses
: Molecular dynamics--Simulation methodsMolecular dynamics--Computer simulationNuclear magnetic resonance spectroscopyBiomolecules--Computer simulationX-ray crystallographyMacromolecules--StructureMolecular dynamicsBiophysicsBiochemistry

28. Identification and Biophysical Characterization of Small Molecules Modulating Protein Disulfide Isomerase in Neurodegenerative Diseases

: Kaplan, Anna
: 2015
: Theses
: Nervous system--DegenerationNeuroprotective agentsProtein disulfide isomeraseBiophysicsBiochemistryBiology

29. Protein Structure Dynamics and Function at Micelle and Particle Interfaces

: Chin, Michael
: 2015
: Theses
: ChemistryBiochemistryBiophysics

30. Winning the cellular lottery: how proteins reach and recognize targets in DNA

: Redding, Sy Eugene
: 2015
: Theses
: Promoters (Genetics)DNA-protein interactionsDNA-binding proteinsBiophysicsBiochemistryBiology

31. Learning from cadherin structures and sequences: affinity determinants and protein architecture

: Felsovalyi, Klara
: 2014
: Theses
: Protein bindingCadherinsBiochemistryBioinformaticsBiophysics

32. Structural and biophysical characterization of protocadherin extracellular regions

: Wolcott, Holly Noelle
: 2014
: Theses
: BiochemistryBiophysics

33. CysZ: Structural and Functional Studies of a Novel Sulfate Transport Protein

: Assur, Zahra
: 2013
: Theses
: CytologyCarrier proteinsBiochemistryBiophysics

34. Orientations and Proximities of the Extracellular Ends of Transmembrane Helices S0 and S4 in Open and Closed BK Potassium Channels

: Niu, Xiaowei; Liu, Guoxia; Wu, Roland; Chudasama, Neelesh; Zakharov, Sergey; Karlin, Arthur; Marx, Steven O.
: 2013
: Articles
: BiochemistryMolecular biologyBiophysicsMedicine

35. Quantification of gait parameters in freely walking wild type and sensory deprived Drosophila melanogaster

: Mendes, Cesar; Bartos, Imre; Akay, Turgay; Marka, Szabolcs; Mann, Richard S.
: 2013
: Articles
: BiochemistryBiophysicsNeurosciences

36. Structural and Functional Studies of Biotin-Dependent Carboxylases

: Huang, Christine S.
: 2013
: Theses
: BiochemistryBiophysics

37. An Analysis of the Essential Chromatin Factor Zinc Finger Protein 1 (ZFP-1), and a Study of the Involvement of RNAi factors in Histone Processing in Caenorabditis Elegans

: Anastasiades Avgousti, Daphne Christina
: 2012
: Theses
: BiochemistryBiophysics

38. Developmental Regulation of Chromatin Conformation by Hox Proteins in Drosophila

: Angelopoulos, Marios; McKay, Daniel J.; Mann, Richard S.
: 2012
: Articles
: BiochemistryBiophysics

39. Mechanochemical Methods for Single Molecule Biochemistry and Studies of Thiol-Disulfide Exchange in Proteins

: Kosuri, Pallav
: 2012
: Theses
: BiophysicsBiochemistryBiology

40. Single-Molecule Analysis of Ribosome and Initiation Factor Dynamics during the Late Stages of Translation Initiation

: MacDougall, Daniel David
: 2012
: Theses
: Genetic translationBiochemistryRibosomesBiophysics

41. The Catalytic Efficiency and Conformational Dynamics of Escherichia coli DNA Repair Enzyme AlkB

: Ergel, Burce
: 2012
: Theses
: BiochemistryBiophysicsOxidoreductasesCatalysisProteins

42. Gates and Latches: the mechanochemistry of ATP binding in kinesin 1 and Eg5

: Behnke-Parks, William M.
: 2011
: Theses
: BiologyBiophysicsBiochemistry

43. Ligand-Protein Interactions in Cytochromes

: Catalano, Jaclyn
: 2011
: Theses
: ChemistryBiochemistryBiophysics

44. The Role of Initiation Factor Dynamics in Translation Initiation

: Elvekrog, Margaret Mary
: 2011
: Theses
: ChemistryBiophysicsBiochemistry

45. Visualizing the One-Dimensional Diffusion of DNA Mismatch Repair Proteins at the Single-Molecule Level

: Gorman, Jason
: 2011
: Theses
: BiologyBiochemistryBiophysics

46. Minimum energy conformations of DNA dimeric subunits: Potential energy calculations for dGpdC, dApdA, dCpdC, dGpdG, and dTpdT

: Broyde, Suse B.; Wartell, Roger M.; Stellman, Steven D.; Hingerty, B.
: 1978
: Articles
: BiochemistryBiophysicsGenetics

47. Influence of ribose 2′-O-methylation on GpC conformation by classical potential energy calculations

: Stellman, Steven D.; Broyde, Suse B.; Wartell, Roger M.
: 1976
: Articles
: BiochemistryBiophysicsGenetics

48. Classical potential energy calculations for ApA, CpC, GpG, and UpU. The influence of the bases on RNA subunit conformations

: Broyde, Suse B.; Wartell, Roger M.; Stellman, Steven D.; Hingerty, Brian; Landridge, Robert
: 1975
: Articles
: BiochemistryBiophysicsGenetics

49. Conformation of a rare nucleoside in the anti-codon loop of tRNAs: Potential energy calculations for 2′-O-methyl cytidine

: Stellman, Steven D.; Hingerty, B.; Broyde, Suse B.; Langridge, R.
: 1975
: Articles
: BiochemistryBiophysicsGenetics

50. Structure of guanylyl-3′,5′-cytidine monophosphate. II. Description of the molecular and crystal structure of the calcium derivative in space group P2₁

: Hingerty, B.; Subramanian, E.; Stellman, Steven D.; Broyde, Suse B.; Sato, T.; Langridge, R.
: 1975
: Articles
: BiochemistryBiophysicsGenetics

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1. Directed Evolution of Protein Receptor Binding for Small Molecule Therapeutics Using Fluorescence Polarization

2. How to steal ribosomes: structural studies of two different internal ribosome entry sites

3. Structural and Biochemical Studies of the Human pre-mRNA 3’-end Processing Complex

4. Investigation of Ribonuclease HI handle region dynamics using Solution-state nuclear magnetic resonance spectroscopy, Molecular Dynamic simulations and X-ray crystallography

5. Structural and Biophysical Studies of Hair Cell Mechanotransduction Proteins

6. The Critical Assessment of Protein Dynamics using Molecular Dynamics (MD) Simulations and Nuclear Magnetic Resonance (NMR) Spectroscopy Experimentation

7. Biomolecular NMR spectroscopy: Application to the study of the piRNA-pathway protein GTSF1, and backbone and side-chain spin relaxation methods development

8. Nucleosome Curtains and their application to the study of DNA condensation by condensin

9. Solving Challenging Structures using Single-Particle Cryogenic Electron Microscopy

10. Using single molecule magnetic tweezers to dissect titin energy release during muscle contraction

11. Allosteric Coupling, Nucleotide Binding and ATP Hydrolysis by Hsp70 Chaperones on a Structural Basis

12. Dynamic Nuclear Polarization with Biradical Affinity Reagents

13. Integration of EGFR and LIN-12/Notch signaling in Vulval Precursor Cell fate specification in Caenorhabditis elegans

14. RNA force field with accuracy comparable to state-of-the-art protein force fields

15. Routine single particle CryoEM sample and grid characterization by tomography

16. Structural and biophysical studies of the Drosophila melanogaster Dpr and DIP families

17. Systematically Mapping the Epigenetic Context Dependence of Transcription Factor Binding

18. The Role of Eukaryotic Recombinase Loop L1 During Homologous Recombination

19. The Saccharomyces cerevisiae Srs2 Helicase Regulates Homologous Recombination through the Disassembly of Recombination Intermediates

20. Cryo-electron microscopy and single particle reconstructions of the Leishmania major ribosome and of the encephalomyocarditis virus internal ribosome entry site bound to the 40S subunit

21. Nanoscale Electrical and Coarse-grained Molecular Dynamics Studies of Influenza Hemagglutinin-mediated Membrane Fusion Pores

22. Regulation of Release Factor 2 in Non-canonical Translation Pathways

23. Single-molecule observations of hRPA, RAD51, and RAD52 on single-stranded DNA

24. Structural and Functional Studies of TRPML1 and TRPP2

25. Cryo-electron microscopy studies of dynamical features of ribosomes during the translation process

26. Oxidative Folding in Bacteria: Studies Using Single Molecule Force Spectroscopy

27. Understanding complex biomolecular systems through the synergy of molecular dynamics simulations, NMR spectroscopy and X-Ray crystallography

28. Identification and Biophysical Characterization of Small Molecules Modulating Protein Disulfide Isomerase in Neurodegenerative Diseases

29. Protein Structure Dynamics and Function at Micelle and Particle Interfaces

30. Winning the cellular lottery: how proteins reach and recognize targets in DNA

31. Learning from cadherin structures and sequences: affinity determinants and protein architecture

32. Structural and biophysical characterization of protocadherin extracellular regions

33. CysZ: Structural and Functional Studies of a Novel Sulfate Transport Protein

34. Orientations and Proximities of the Extracellular Ends of Transmembrane Helices S0 and S4 in Open and Closed BK Potassium Channels

35. Quantification of gait parameters in freely walking wild type and sensory deprived Drosophila melanogaster

36. Structural and Functional Studies of Biotin-Dependent Carboxylases

37. An Analysis of the Essential Chromatin Factor Zinc Finger Protein 1 (ZFP-1), and a Study of the Involvement of RNAi factors in Histone Processing in Caenorabditis Elegans

38. Developmental Regulation of Chromatin Conformation by Hox Proteins in Drosophila

39. Mechanochemical Methods for Single Molecule Biochemistry and Studies of Thiol-Disulfide Exchange in Proteins

40. Single-Molecule Analysis of Ribosome and Initiation Factor Dynamics during the Late Stages of Translation Initiation

41. The Catalytic Efficiency and Conformational Dynamics of Escherichia coli DNA Repair Enzyme AlkB

42. Gates and Latches: the mechanochemistry of ATP binding in kinesin 1 and Eg5

43. Ligand-Protein Interactions in Cytochromes

44. The Role of Initiation Factor Dynamics in Translation Initiation

45. Visualizing the One-Dimensional Diffusion of DNA Mismatch Repair Proteins at the Single-Molecule Level

46. Minimum energy conformations of DNA dimeric subunits: Potential energy calculations for dGpdC, dApdA, dCpdC, dGpdG, and dTpdT

47. Influence of ribose 2′-O-methylation on GpC conformation by classical potential energy calculations

48. Classical potential energy calculations for ApA, CpC, GpG, and UpU. The influence of the bases on RNA subunit conformations

49. Conformation of a rare nucleoside in the anti-codon loop of tRNAs: Potential energy calculations for 2′-O-methyl cytidine

50. Structure of guanylyl-3′,5′-cytidine monophosphate. II. Description of the molecular and crystal structure of the calcium derivative in space group P2₁