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2. Small molecules modulating ferroptosis in disease models
3. Structural and Functional Studies of CNG channels
4. Structure and Function of Glutamate Receptor-Like Channels (GLRs)
5. Structure and Neutralization of Viral Fusion Proteins
6. The role of ER-mitochondria contact sites in the regulation of glucose metabolism: a tale of two mitochondria and its relevance to amyotrophic lateral sclerosis
7. Lipids on Fire: Identifying and Targeting Subcellular Membranes that Drive Ferroptosis
8. Molecular Insights into Ferroptosis as a Therapeutic Target for Huntington’s Disease
9. Structural studies on bestrophin anion channels by cryogenic electron microscopy
10. The Role of Chromatin in Olfaction
11. A p53-independent role for MDM2-MDMX in cell cycle progression
12. Directed Evolution of Protein Receptor Binding for Small Molecule Therapeutics Using Fluorescence Polarization
13. Discovery of Novel Ferroptosis Regulators Using Genetic and Lipidomic Analyses
14. How to steal ribosomes: structural studies of two different internal ribosome entry sites
15. Novel Functions for Dynein Adaptor RILP in Neuronal Autophagy
16. Structural and Biochemical Studies of the Human pre-mRNA 3’-end Processing Complex
17. Structural and functional characterization of the retinol-binding protein receptor STRA6
18. Structure and Function of a Transposon-Encoded CRISPR-Cas System
19. Visualizing cell surface interactions using cryogenic electron microscopy
20. Atf5 Links Olfactory Receptor Induced Stress Response to Proper Neuronal Function
21. Expanding Silane-Mediated Coupling Methodologies for the Formation of Medicinally Relevant Structural Motifs
22. Investigation of Ribonuclease HI handle region dynamics using Solution-state nuclear magnetic resonance spectroscopy, Molecular Dynamic simulations and X-ray crystallography
23. Structural and Biophysical Studies of Hair Cell Mechanotransduction Proteins
24. The Critical Assessment of Protein Dynamics using Molecular Dynamics (MD) Simulations and Nuclear Magnetic Resonance (NMR) Spectroscopy Experimentation
25. The Regulation of Mitochondrial Complex I Biogenesis in Drosophila Flight Muscles
26. Biomolecular NMR spectroscopy: Application to the study of the piRNA-pathway protein GTSF1, and backbone and side-chain spin relaxation methods development
27. Genetic Mechanisms of Regulated Stochastic Gene Expression
28. Liver X Receptor cis-Repression and Cholesterol Efflux Restrain Innate Immunity and Coronary Artery Disease
29. Mechanisms and therapeutic targeting of NT5C2 mutations in relapsed acute lymphoblastic leukemia
30. Molecular Approaches to Targeting Oncogenic KRAS and Ferroptosis
31. Novel functions of C9ORF72, a gene involved in ALS/FTD
32. Nucleosome Curtains and their application to the study of DNA condensation by condensin
33. Solving Challenging Structures using Single-Particle Cryogenic Electron Microscopy
34. Structural Analyses of the Transient Receptor Potential Channels TRPV3 and TRPV6
35. Structural Investigation of Plasmodium falciparum Chloroquine Resistance Transporter in the Context of Anti-Malarial Drug Resistance
36. Structural studies of the yeast transcription termination complex Nrd1-Nab3-Sen1
37. The Mechanism of NusG-Mediated Transcription-Translation Coupling and The Role of RacR in Transcription Regulation in Escherichia coli
38. Using single molecule magnetic tweezers to dissect titin energy release during muscle contraction
39. Allosteric Coupling, Nucleotide Binding and ATP Hydrolysis by Hsp70 Chaperones on a Structural Basis
40. Characterization of a novel Ser/Thr kinase/phosphatase pair in Escherichia coli
41. Characterization of the human homozygous R182W POLG2 mutation in mitochondrial DNA depletion syndrome
42. Crk proteins transduce FGF signaling to promote lens fiber cell elongation
43. Design and Synthesis of 3'-Oxygen-Modified Cleavable Nucleotide Reversible Terminators for Scarless DNA Sequencing by Synthesis
44. Development of Single Molecule Electronic SNP Assays using Polymer Tagged Nucleotides and Nanopore Detection
45. Dual tRNA mimicry in the Cricket Paralysis Virus IRES uncovers an unexpected similarity with the Hepatitis C Virus IRES
46. Dynamic Nuclear Polarization with Biradical Affinity Reagents
47. Functional odor classification through a medicinal chemistry approach
48. Integration of EGFR and LIN-12/Notch signaling in Vulval Precursor Cell fate specification in Caenorhabditis elegans
49. Pathways for kidney triglyceride accumulation
50. Resonance-energy-transfer-based fluorescence imaging and free energy perturbation calculation
51. RNA force field with accuracy comparable to state-of-the-art protein force fields
52. Routine single particle CryoEM sample and grid characterization by tomography
53. Shared Molecular Features of Inherited and Sporadic ALS/FTD
54. Structural and biophysical studies of the Drosophila melanogaster Dpr and DIP families
55. Structural and Functional Investigation of Bacterial Membrane Biosynthesis
56. Structural Studies of the Integrator Complex -- pre-UsnRNA 3'-end Processing Machinery
57. Systematically Mapping the Epigenetic Context Dependence of Transcription Factor Binding
58. Targeting neurons with small molecule probes: from imaging to modulation
59. The BARD1 BRCT Domain in Tumor Suppression and Genome Stability
60. The Role of Eukaryotic Recombinase Loop L1 During Homologous Recombination
61. The Role of Modified UNC-68 in Age-related Caenorhabditis elegans Muscle Function Loss
62. The Saccharomyces cerevisiae Srs2 Helicase Regulates Homologous Recombination through the Disassembly of Recombination Intermediates
63. Viral Entry Properties Required for Fitness in Humans Are Lost through Rapid Genomic Change during Viral Isolation
64. Artificial Metabolons: Design of Self-Assembled Bio-Complexes
65. Biochemical and Genetic Investigation of Immature Murine Leukemia Virus Assembly
66. Biology of maintenance and de novo methylation mediated by DNA methyltransferase-1
67. Correction of Monogenic and Common Retinal Disorders with Gene Therapy
68. Cryo-electron microscopy and single particle reconstructions of the Leishmania major ribosome and of the encephalomyocarditis virus internal ribosome entry site bound to the 40S subunit
69. Engineering Electron Transfer Processes in Oxidoreductases: Applications in Biocatalysis
70. Excited-State Dynamics of the Thiopurine Prodrug 6-Thioguanine: Can N9-Glycosylation Affect Its Phototoxic Activity?
71. Expression of Calgranulin Genes S100A8, S100A9 and S100A12 Is Modulated by n-3 PUFA during Inflammation in Adipose Tissue and Mononuclear Cells
72. Fragility of foot process morphology in kidney podocytes arises from chaotic spatial propagation of cytoskeletal instability
73. GWAS for serum galactose-deficient IgA1 implicates critical genes of the O-glycosylation pathway
74. How and when does an anticancer drug leave its binding site?
75. Influence of Substituent Chain Branching on the Transfection Efficacy of Cyclopropenium-Based Polymers
76. Intracellular calcium release channels: an update
77. Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting
78. Meiotic failure in cyclin A1-deficient mouse spermatocytes triggers apoptosis through intrinsic and extrinsic signaling pathways and 14-3-3 proteins
79. Membrane partitioning by Flotillin-1 facilitates amphetamine-induced dopamine transporter activity
80. Nanoscale Electrical and Coarse-grained Molecular Dynamics Studies of Influenza Hemagglutinin-mediated Membrane Fusion Pores
81. Physiology and pathophysiology of excitation–contraction coupling in skeletal muscle: the functional role of ryanodine receptor
82. PTEN affects gene expression and histone modifications and plays a role in the regulation of transcription
83. Regulation of Release Factor 2 in Non-canonical Translation Pathways
84. RPGRIP1L and FTO – genes implicated in the effects of FTO intronic sequence variants on food intake – also affect adipogenesis and adipocyte biology.
85. Sequence-based prediction of permissive stretches for internal protein tagging and knockdown
86. Single-molecule observations of hRPA, RAD51, and RAD52 on single-stranded DNA
87. Stem Cell Therapies in Retinal Disorders
88. Structural and Functional Studies of TRPML1 and TRPP2
89. Structural and functional studies on the regulation of pyruvate carboxylase by the bacterial second messenger cyclic-di-AMP
90. Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape
91. Weight Perturbation Alters Leptin Signal Transduction in a Region-Specific Manner throughout the Brain
92. Case report: Severe central nervous system manifestations associated with aberrant efavirenz metabolism in children: the role of CYP2B6 genetic variation
93. Chloride Intracellular Channels 1 and 4 function in distinct branches of S1P signaling to regulate endothelial cell behavior and vascular development
94. Cryo-electron microscopy studies of dynamical features of ribosomes during the translation process
95. Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8
96. Donor CD47 controls T cell alloresponses and is required for tolerance induction following hepatocyte allotransplantation
97. Examining the Effects of D-Amino Acids on Translation
98. Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory
99. Focused ultrasound-enhanced intranasal brain delivery of brain-derived neurotrophic factor
100. Formin DAAM1 Organizes Actin Filaments in the Cytoplasmic Nodal Actin Network
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