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1. Lipids on Fire: Identifying and Targeting Subcellular Membranes that Drive Ferroptosis

Von Krusenstiern, Alfred Nikolai
2022
Theses
BiochemistryCell deathLipids--PeroxidationCancer--TreatmentEndoplasmic reticulumFatty acidsRaman effectConfocal fluorescence microscopy

2. A p53-independent role for MDM2-MDMX in cell cycle progression

Klein, Alyssa Michelle
2021
Theses
CytologyMolecular biologyBiochemistryCancerMutation

3. Structural and functional characterization of the retinol-binding protein receptor STRA6

Costabile, Brianna Kay
2021
Theses
BiochemistryEpitheliumVitamin A deficiencyVitamin APlacentaChoroid plexusElectron microscopyCalmodulin--Physiological effectZebra danio

4. Structure and Function of a Transposon-Encoded CRISPR-Cas System

Halpin-Healy, Tyler Sheehan
2021
Theses
BiochemistryBiophysicsMolecular biologyVibrio choleraeRNADNA

5. Visualizing cell surface interactions using cryogenic electron microscopy

Rapp, Micah
2021
Theses
BiophysicsBiochemistryElectron microscopyCOVID-19 (Disease)Low temperature engineeringCell membranesCell receptorsImmunoglobulins

6. Liver X Receptor cis-Repression and Cholesterol Efflux Restrain Innate Immunity and Coronary Artery Disease

Thomas, David George
2019
Theses
CytologyMolecular biologyBiochemistryAtherosclerosis--PreventionImmunityNuclear receptors (Biochemistry)

7. Mechanisms and therapeutic targeting of NT5C2 mutations in relapsed acute lymphoblastic leukemia

Dieck, Chelsea
2019
Theses
BiochemistryLymphoblastic leukemiaDrug resistanceOncologyMutation (Biology)Molecular biology

8. Structural Analyses of the Transient Receptor Potential Channels TRPV3 and TRPV6

McGoldrick, Luke Lawrence Reedy
2019
Theses
BiochemistryMolecular biologyTRP channelsStructure-activity relationships (Biochemistry)Ion channels

9. Using single molecule magnetic tweezers to dissect titin energy release during muscle contraction

Eckels, Edward Charles
2019
Theses
BiophysicsBiochemistryPhysiologyMagnetic tweezersMuscle contractionProtein folding

10. Systematically Mapping the Epigenetic Context Dependence of Transcription Factor Binding

Kribelbauer, Judith Franziska
2018
Theses
BiochemistryBioinformaticsBiophysicsTranscription factorsGene regulatory networksEpigenetics

11. The BARD1 BRCT Domain in Tumor Suppression and Genome Stability

Billing, David
2018
Theses
Molecular biologyCytologyBiochemistryTumor suppressor proteinsGenomes

12. The Role of Eukaryotic Recombinase Loop L1 During Homologous Recombination

Steinfeld, Justin Benjamin
2018
Theses
BiophysicsBiochemistryGeneticsGenetic recombinationEukaryotic cells

13. Membrane partitioning by Flotillin-1 facilitates amphetamine-induced dopamine transporter activity

Fong, Wendy Mei
2017
Theses
BiochemistryNeurosciencesCytologyCell membranesCarrier proteins

14. PTEN affects gene expression and histone modifications and plays a role in the regulation of transcription

Steinbach, Nicole
2017
Theses
CytologyBiochemistryOncologyGene expressionGenetic transcription

15. Single-molecule observations of hRPA, RAD51, and RAD52 on single-stranded DNA

Ma, Chu Jian
2017
Theses
BiochemistryBiophysicsDNA replicationGenetic recombinationMolecular biology

16. Chloride Intracellular Channels 1 and 4 function in distinct branches of S1P signaling to regulate endothelial cell behavior and vascular development

Jilishitz, Irina
2016
Theses
MorphogenesisGrowth factorsNeovascularizationEndothelial cellsMolecular biologyBiochemistry

17. Investigating the role of the RNA binding protein TDP-43 in Amyotrophic Lateral Sclerosis using animal and cell-based models of disease

Lehrer, Helaina
2015
Theses
Molecular biologyNeurosciencesBiochemistry

18. Reprogramming protein synthesis for cell engineering

Anzalone, Andrew Vito
2015
Theses
Proteins--SynthesisBioengineeringAmino acids--BiotechnologyRNA-protein interactionsSynthetic biologyBiochemistryChemistry, OrganicBiologyMolecular biology

19. PTEN-LONG, a translational variant of the canonical tumor suppressor PTEN

Hopkins, Benjamin
2013
Theses
BiologyBiochemistryTumor suppressor proteinsAdenocarcinomaPancreas--Cancer--Research

20. Ferroptosis: A Novel Form of Cancer Cell Death Induced by the Small Molecule Erastin

Lemberg, Kathryn
2011
Theses
BiologyBiochemistryChemistryApoptosisCell deathCancer

21. The Ribosome Discriminates the Structure of the Amino Acid at its Peptidyl-Transferase Center

Englander, Michael Thomas
2011
Theses
BiochemistryRibosomesAmino acidsCrick, Francis, 1916-2004