Academic Unit: Biochemistry and Molecular Biophysics / Type: Articles / Language: English | Search Results

1. Abl Family Tyrosine Kinases Are Essential for Basement Membrane Integrity and Cortical Lamination in the Cerebellum

: Qiu, Zhaozhu; Cang, Yong; Goff, Stephen P.
: 2010
: Articles
: Molecular biologyNeurosciencesMicrobiology

2. Abl-interactor-1, A Novel SH3 Protein Binding to the Carboxy-terminal Portion of the Abl Protein, Suppresses v-abl Transforming Activity

: Shi, Yanggu; Alin, Kimona; Goff, Stephen P.
: 1995
: Articles
: CytologyGeneticsVirology

3. Accelerating the Original Profile Kernel

: Hamp, Tobias; Goldberg, Tatyana; Rost, Burkhard
: 2013
: Articles
: Pattern recognition systemsKernel functionsProteins--Analysis--MethodologyMolecular biology

4. Accurate and sensitive quantification of protein-DNA binding affinity

: Rastogi, Chaitanya; Rube, Hans Tomas; Kribelbauer, Judith Franziska; Crocker, Justin; Loker, Ryan Edmund; Martini, Gabriella D.; Laptenko, Oleg; Freed-Pastor, William Allen; Prives, Carol L.; Stern, David L.; Mann, Richard S.; Bussemaker, Harmen J.
: 2018
: Articles
: Transcription factorsDNA-protein interactionsProtein bindingProbabilities--Mathematical models

5. Accurate proteome-wide protein quantification from high-resolution 15N mass spectra

: Kryglyak, Leonid; Singh, Mona; Perlman, David H.; Tavazoie, Saeed; Caudy, Amy A.; Ruse, Christian; Amini, Sasan; Bloom, Joshua S.; Khan, Zia
: 2011
: Articles
: BiochemistryMolecular biology

6. A computational interactome and functional annotation for the human proteome

: Garzon Canas, Jose I.; Deng, Lei; Murray, Diana; Shapira, Sagi; Petrey, Donald S.; Honig, Barry
: 2016
: Articles
: Computational biologyProteomicsProtein-protein interactionsSystems biology

7. Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G

: Li, Wen; Liu, Zheng; Koripella, Ravi Kiran; Langlois, Robert; Sanyal, Suparna; Frank, Joachim
: 2015
: Articles
: HydrolysisRibosomesGuanosine triphosphataseMolecular biologyBiochemistry

8. A High-Throughput Strategy for Dissecting Mammalian Genetic Interactions

: Stockman, Victoria B.; Ghamsari, Lila; Lasso Cabrera, Gorka; Honig, Barry; Shapira, Sagi; Wang, Harris H.
: 2016
: Articles
: RNAMammals--Molecular geneticsNucleotide sequenceSystems biologyMolecular geneticsCloningGeneticsBiology--Classification

9. A Kazal-Type Serine Protease Inhibitor from the Defense Gland Secretion of the Subterranean Termite Coptotermes formosanus Shiraki

: Negulescu, Horia; Guo, Youzhong; Garner, Thomas P.; Goodwin, Octavia Y.; Henderson, Gregg; Laine, Roger A.; Macnaughtan, Megan A.
: 2015
: Articles
: Proteins--StructureProteins--SecretionRhinotermitidaeAmino acid sequenceProtease inhibitorsFormosan subterranean termiteBiochemistryEntomology

10. Allele-Specific Knockdown of ALS-Associated Mutant TDP-43 in Neural Stem Cells Derived from Induced Pluripotent Stem Cells

: Nishimura, Agnes L.; Scotter, Emma L.; Abdelgany, Amr; Shum, Carole; Sardone, Valentina; Wright, Jamie; Lee, Youn-Bok; Chen, Han-Jou; Bilican, Bilada; Carrasco, Monica; Maniatis, Tom; Chandran, Siddharthan; Gallo, Jean-Marc; Rogelj, Boris; Shaw, Christopher E.
: 2014
: Articles
: Neural stem cellsCell differentiationSmall interfering RNAMorphology

11. ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function

: Sharma, Aarti; Lyashchenko, Alexander K.; Lu, Lei; Ebrahimi Nasrabady, Sara; Elmaleh, Margot; Mendelsohn, Monica; Nemes, Adriana; Tapia, Juan Carlos; Mentis, George Z.; Shneider, Neil
: 2016
: Articles
: Nervous system--Degeneration--Molecular aspectsAmyotrophic lateral sclerosisNeurologyMedicineMolecular biologyNeurosciences

12. An Automated Microwell Platform for Large-Scale Single Cell RNA-Seq

: Yuan, Jinzhou; Sims, Peter A.
: 2016
: Articles
: Nucleotide sequenceGene expression

13. A Sixth Modality of Infectious Disease: Contagious Cancer from Devils to Clams and Beyond

: Metzger, Michael; Goff, Stephen P.
: 2016
: Articles
: Parasites--EvolutionCancerImmunologic diseasesEpidemiology

14. Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy

: Serio, Andrea; Bilican, Bilada; Barmada, Sami J.; Ando, Dale Michael; Zhao, Chen; Siller, Rick; Burr, Karen; Haghi, Ghazal; Story, David; Nishimura, Agnes Lumi; Carrasco, Monica A.; Phatnani, Hemali P.; Shum, Carole; Wilmut, Ian; Maniatis, Tom; Shaw, Christopher E.; Finkbeiner, Steven; Chandran, Siddharthan
: 2013
: Articles
: NeurosciencesBiochemistry

15. A Survey of 6,300 Genomic Fragments for cis-Regulatory Activity in the Imaginal Discs of Drosophila melanogaster

: Jory, Aurelie E.; Estella, Carlos; Giorgianni, Matt W.; Slattery, Matthew; Laverty, Todd R.; Rubin, Gerald M.; Mann, Richard S.
: 2012
: Articles
: Genetics

16. Asynchronous Transcriptional Silencing of Individual Retroviral Genomes in Embryonic Cells

: Schlesinger, Sharon; Meshorer, Eran; Goff, Stephen P.
: 2014
: Articles
: CytologyGeneticsVirology

17. A transformation-defective mutant of Abelson murine leukemia virus lacks protein kinase activity

: Witte, Owen N.; Goff, Stephen P.; Rosenberg, Naomi; Baltimore, David
: 1980
: Articles
: Retroviruses--EnzymesMolecular biologyMitogen-activated protein kinasesVirologyMicrobiology

18. Bacterial Adaptation through Loss of Function

: Hottes, Alison K.; Freddolino, Peter L.; Khare, Anupama; Donnell, Zachary N.; Liu, Julia C.; Tavazoie, Saeed
: 2013
: Articles
: Microbial mutationNonsense mutationBacteriaGeneticsMicrobiologyBiology--Classification

19. Balance Control Mediated by Vestibular Circuits Directing Limb Extension or Antagonist Muscle Co-activation

: Murray, Andrew; Croce, Katherine; Belton, Timothy; Akay, Turgay; Jessell, Thomas M.
: 2018
: Articles
: Motor ability--Physiological aspectsMotor ability--TestingNeurochemistryMolecular biologyVestibular nucleiEquilibrium (Physiology)Neurosciences

20. C-Abl Is Required for the Development of Hyperoxia-Induced Retinopathy

: Nunes, Irene; Zanetta, Lucia; Higgins, Rosemary D.; Shamamian, Peter; Goff, Stephen P.
: 2001
: Articles
: BiochemistryOphthalmologyMedicine

21. Cell type-specific CLIP reveals that NOVA regulates cytoskeleton interactions in motoneurons

: Yuan, Yuan; Xie, Shirley; Darnell, Jennifer C.; Darnell, Andrew J.; Saito, Yuhki; Phatnani, Hemali P.; Murphy, Elisabeth A.; Zhang, Chaolin; Maniatis, Tom; Darnell, Robert B.
: 2018
: Articles
: Motor neuronsCytoskeletonSeptinsRNA splicingBiology

22. cis-regulatory architecture of a short-range EGFR organizing center in the Drosophila melanogaster leg

: Newcomb, Susan Elizabeth; Voutev, Roumen; Jory, Aurelie E.; Delker, Rebecca; Slattery, Matthew; Mann, Richard S.
: 2018
: Articles
: Drosophila melanogaster--GeneticsGrowth factors--ReceptorsCloningBiologyGene expression

23. Concentration-Dependent Exchange of Replication Protein A on Single-Stranded DNA Revealed by Single-Molecule Imaging

: Gibb, Bryan; Ye, Ling Feng; Gergoudis, Stephanie C.; Kwon, YoungHo; Niu, Hengyao; Sung, Patrick; Greene, Eric C.
: 2014
: Articles
: Protein bindingDNA--MetabolismSaccharomyces cerevisiae--GeneticsGenetics

24. Construction of mutants of Moloney murine leukemia virus by suppressor-linker insertional mutagenesis: positions of viable insertion mutations

: Lobel, Leslie I.; Goff, Stephen P.
: 1984
: Articles
: Insertional mutagenesisMouse leukemia virusesAntioncogenesImmunologyMicrobiologyGenetics

25. Cooperative interactions enable singular olfactory receptor expression in mouse olfactory neurons

: Monahan, Kevin; Schieren, Ira; Cheung, Jonah; Mumbey-Wafula, Alice Mary; Monuki, Edwin S.; Lomvardas, Stavros
: 2017
: Articles
: GeneticsOlfactory receptor genesGene expressionOlfactory nerve

26. Correlating protein function and stability through the analysis of single amino acid substitutions

: Bromberg, Yana; Rost, Burkhard
: 2009
: Articles
: BioinformaticsBiochemistry

27. Determination of the Critical Concentration of Neutrophils Required to Block Bacterial Growth in Tissues

: Li, Yongmei; Karlin, Arthur; Loike, John D.; Silverstein, Samuel C.
: 2004
: Articles
: Bacterial growthBiophysics--ResearchNeutrophilsMedicineMicrobiologyMolecular biology

28. Developing a molecular dynamics force field for both folded and disordered protein states

: Robustelli, Paul; Piana, Stefano; Shaw, David Elliot
: 2018
: Articles
: Molecular dynamicsComputer simulationProteinsProtein folding

29. Developmental control of lateralized neuron size in the nematode Caenorhabditis elegans

: Lockery, Shawn; Hobert, Oliver; Goldsmith, Andrew; Sarin, Sumeet
: 2010
: Articles
: NeurosciencesMolecular biology

30. Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8

: Soto, Cinque; Ofek, Gilad; Joyce, M. Gordon; Zhang, Baoshan; McKee, Krisha; Longo, Nancy S.; Yang, Yongping; Huang, Jinghe; Parks, Robert; Eudailey, Joshua; Lloyd, Krissey E.; Alam, S. Munir; Haynes, Barton F.; Mullikin, James C.; Connors, Mark; Mascola, John R.; Shapiro, Lawrence S.; Kwong, Peter D.; NISC Comparative Sequencing Program
: 2016
: Articles
: Neutralization (Chemistry)ImmunoglobulinsPhylogenyHIV infectionsBiochemistryBiology

31. Developmental Regulation of Chromatin Conformation by Hox Proteins in Drosophila

: Angelopoulos, Marios; McKay, Daniel J.; Mann, Richard S.
: 2012
: Articles
: BiochemistryBiophysics

32. Differential effects of natural rewards and pain on vesicular glutamate transporter expression in the nucleus accumbens

: Manders, Toby R.; Ziff, Edward B.; Wang, Jing; Turkey, David S.; Lee, Michelle; Xu, Duo; Eberle, Sarah E.; Goffer, Yossef
: 2013
: Articles
: BiochemistryNeurosciences

33. Distinctive Genes Determine Different Intramuscular Fat and Muscle Fiber Ratios of the longissimus dorsi Muscles in Jinhua and Landrace Pigs

: Wu, Ting; Zhang, Zhenhai; Yuan, Zhanqin; Lo, Li Jan; Chen, Jun; Wang, Yizhen; Peng, Jinrong
: 2013
: Articles
: Swine--GeneticsMeat--QualityGene expressionGenetic regulationSwine--AnatomyGeneticsVeterinary medicine

34. Distinct Roles of c-Abl and Atm in Oxidative Stress Response Are Mediated by Protein Kinase C δ

: Goff, Stephen P.; Nakayama, Keiko; Nakayama, Keiichi I.; Boast, Sharon; Ishii, Tetsuro; Hu, Yuanyu; Rasheed, Naslin; Wang, Xueying; Li, Baojie
: 2004
: Articles
: Molecular biologyGenetics

35. Divergent Transcriptional Regulatory Logic at the Intersection of Tissue Growth and Developmental Patterning

: Slattery, Matthew; Voutev, Roumen; Ma, Lijia; Nègre, Nicolas; White, Kevin P.; Mann, Richard S.
: 2013
: Articles
: Genetic transcription--RegulationDevelopmental biologyDevelopmental geneticsTissues--GrowthGeneticsMolecular biology

36. Domain structure of the Moloney murine leukemia virus reverse transcriptase: mutational analysis and separate expression of the DNA polymerase and RNase H activities

: Tanese, Naoko; Goff, Stephen P.
: 1988
: Articles
: Mouse leukemia virusesRetroviruses--GeneticsRecombinant proteinsBiochemistryInsertional mutagenesis

37. Dual tRNA mimicry in the Cricket Paralysis Virus IRES uncovers an unexpected similarity with the Hepatitis C Virus IRES

: Pisareva, Vera P.; Pisarev, Andrey V.; Fernández, Israel S.
: 2018
: Articles
: VirologyRNAHepatitis C virusBiochemistry

38. DWARF – a data warehouse system for analyzing protein families

: Fischer, Markus; Thai, Quan; Grieb, Melanie; Pleiss, Jürgen
: 2006
: Articles
: Proteins--Data processingProtein engineeringBioengineering--Data processingData warehousingBioinformatics

39. Dynamic Instability of Genomic Methylation Patterns in Pluripotent Stem Cells

: Ooi, Steen K. T.; Wolf, Daniel; Hartung, Odelya; Agarwal, Suneet; Daley, George Q.; Goff, Stephen P.; Bestor, Timothy H.
: 2010
: Articles
: GeneticsMolecular biologyBiochemistry

40. Efferent Vestibular Neurons Show Homogenous Discharge Output But Heterogeneous Synaptic Input Profile In Vitro

: Mathews, Miranda A.; Murray, Andrew; Wijesinghe, Rajiv; Cullen, Karen; Tung, Victoria W. K.; Camp, Aaron J.
: 2015
: Articles
: NeuronsAction potentials (Electrophysiology)Neural transmissionMembrane potentials (Electrophysiology)Vestibular nucleiNeurosciences

41. Elucidating synergistic dependencies in lung adenocarcinoma by proteome-wide signaling-network analysis

: Bansal, Mukesh; He, Jing; Peyton, Michael; Kustagi, Manjunath; Iyer, Archana; Comb, Michael; White, Michael; Minna, John D.; Califano, Andrea
: 2019
: Articles
: AdenocarcinomaMolecular biologyLungs--Cancer--Molecular aspectsProteomics

42. Embryonic Lethality in Mice Homozygous for a Targeted Disruption of the N-myc Gene

: Charron, Jean; Malynn, Barbara A.; Fisher, Peter; Stewart, Valerie; Jeannotte, Lucie; Goff, Stephen P.; Robertson, Elizabeth J.; Alt, Frederick W.
: 1992
: Articles
: CytologyMolecular biology

43. Endophilins interact with Moloney murine leukemia virus Gag and modulate virion production

: Wang, Margaret; Kim, Wankee; Gao, Guangxia; Torrey, Ted; Morse, Herbert; De Camilli, Pietro; Goff, Stephen P.
: 2003
: Articles
: Molecular biologyVirology

44. Endophilins Interact with Moloney Murine Leukemia Virus Gag and Modulate Virion Production.

: Wang, Margaret Q.; Kim, Wankee; Gao, Guangxia; Morse, Herbert C.; De Camilli, Pietro; Goff, Stephen P.; Torrey, Ted A.
: 2003
: Articles
: Molecular biologyOncologyVirology

45. Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme

: Zhang, Zhening; Liang, Wenguang G.; Bailey, Lucas J.; Tan, Yong Zi; Wei, Hui; Wang, Andrew; Farcasanu, Mara; Woods, Virgil A.; McCord, Lauren A.; Lee, David; Shang, Weifeng; Deprez-Poulain, Rebecca; Deprez, Benoit; Liu, David R.; Koide, Akiko; Koide, Shohei; Kossiakoff, Anthony A.; Li, Sheng; Carragher, Bridget; Potter, Clinton; Tang, Wei-Jen
: 2018
: Articles
: Molecular biologyInsulinPeptidesProteolytic enzymesBiophysics

46. ERK Phosphorylates p66shcA on Ser36 and Subsequently Regulates p27^kip1 Expression via the Akt-FOXO3a Pathway: Implication of p27^kip1 in Cell Response to Oxidative Stress

: Hu, Yuanyu; Wang, Xueying; Zeng, Li; Cai, De-Yu; Sabapathy, Kanaga; Goff, Stephen P.; Firpo, Eduardo J.; Li, Baojie
: 2005
: Articles
: Molecular biologyCytology

47. Estimation of the 3D Variance-Covariance Map in Cryo-Electron Microscopy

: Liao, Hstau Y.; Hashem, Yaser; Frank, Joachim
: 2010
: Articles
: Molecular biology

48. Expression of enzymatically active reverse transcriptase in Escherichia coli

: Tanese, Naoko; Roth, Monica; Goff, Stephen P.
: 1985
: Articles
: Genetic transcription--ResearchMouse leukemia virusesCatalytic RNAMolecular biologyBiochemistry

49. ExpressionPlot: a web-based framework for analysis of RNA-Seq and microarray gene expression data

: Friedman, Brad; Maniatis, Tom
: 2011
: Articles
: StatisticsBioinformatics

50. From DNA to proteins via the ribosome: Structural insights into the workings of the translation machinery

: Frank, Joachim; Agirrezabala, Xabier
: 2010
: Articles
: GeneticsMolecular biology

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1. Abl Family Tyrosine Kinases Are Essential for Basement Membrane Integrity and Cortical Lamination in the Cerebellum

2. Abl-interactor-1, A Novel SH3 Protein Binding to the Carboxy-terminal Portion of the Abl Protein, Suppresses v-abl Transforming Activity

3. Accelerating the Original Profile Kernel

4. Accurate and sensitive quantification of protein-DNA binding affinity

5. Accurate proteome-wide protein quantification from high-resolution 15N mass spectra

6. A computational interactome and functional annotation for the human proteome

7. Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G

8. A High-Throughput Strategy for Dissecting Mammalian Genetic Interactions

9. A Kazal-Type Serine Protease Inhibitor from the Defense Gland Secretion of the Subterranean Termite Coptotermes formosanus Shiraki

10. Allele-Specific Knockdown of ALS-Associated Mutant TDP-43 in Neural Stem Cells Derived from Induced Pluripotent Stem Cells

11. ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function

12. An Automated Microwell Platform for Large-Scale Single Cell RNA-Seq

13. A Sixth Modality of Infectious Disease: Contagious Cancer from Devils to Clams and Beyond

14. Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy

15. A Survey of 6,300 Genomic Fragments for cis-Regulatory Activity in the Imaginal Discs of Drosophila melanogaster

16. Asynchronous Transcriptional Silencing of Individual Retroviral Genomes in Embryonic Cells

17. A transformation-defective mutant of Abelson murine leukemia virus lacks protein kinase activity

18. Bacterial Adaptation through Loss of Function

19. Balance Control Mediated by Vestibular Circuits Directing Limb Extension or Antagonist Muscle Co-activation

20. C-Abl Is Required for the Development of Hyperoxia-Induced Retinopathy

21. Cell type-specific CLIP reveals that NOVA regulates cytoskeleton interactions in motoneurons

22. cis-regulatory architecture of a short-range EGFR organizing center in the Drosophila melanogaster leg

23. Concentration-Dependent Exchange of Replication Protein A on Single-Stranded DNA Revealed by Single-Molecule Imaging

24. Construction of mutants of Moloney murine leukemia virus by suppressor-linker insertional mutagenesis: positions of viable insertion mutations

25. Cooperative interactions enable singular olfactory receptor expression in mouse olfactory neurons

26. Correlating protein function and stability through the analysis of single amino acid substitutions

27. Determination of the Critical Concentration of Neutrophils Required to Block Bacterial Growth in Tissues

28. Developing a molecular dynamics force field for both folded and disordered protein states

29. Developmental control of lateralized neuron size in the nematode Caenorhabditis elegans

30. Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8

31. Developmental Regulation of Chromatin Conformation by Hox Proteins in Drosophila

32. Differential effects of natural rewards and pain on vesicular glutamate transporter expression in the nucleus accumbens

33. Distinctive Genes Determine Different Intramuscular Fat and Muscle Fiber Ratios of the longissimus dorsi Muscles in Jinhua and Landrace Pigs

34. Distinct Roles of c-Abl and Atm in Oxidative Stress Response Are Mediated by Protein Kinase C δ

35. Divergent Transcriptional Regulatory Logic at the Intersection of Tissue Growth and Developmental Patterning

36. Domain structure of the Moloney murine leukemia virus reverse transcriptase: mutational analysis and separate expression of the DNA polymerase and RNase H activities

37. Dual tRNA mimicry in the Cricket Paralysis Virus IRES uncovers an unexpected similarity with the Hepatitis C Virus IRES

38. DWARF – a data warehouse system for analyzing protein families

39. Dynamic Instability of Genomic Methylation Patterns in Pluripotent Stem Cells

40. Efferent Vestibular Neurons Show Homogenous Discharge Output But Heterogeneous Synaptic Input Profile In Vitro

41. Elucidating synergistic dependencies in lung adenocarcinoma by proteome-wide signaling-network analysis

42. Embryonic Lethality in Mice Homozygous for a Targeted Disruption of the N-myc Gene

43. Endophilins interact with Moloney murine leukemia virus Gag and modulate virion production

44. Endophilins Interact with Moloney Murine Leukemia Virus Gag and Modulate Virion Production.

45. Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme

46. ERK Phosphorylates p66shcA on Ser36 and Subsequently Regulates p27^kip1 Expression via the Akt-FOXO3a Pathway: Implication of p27^kip1 in Cell Response to Oxidative Stress

47. Estimation of the 3D Variance-Covariance Map in Cryo-Electron Microscopy

48. Expression of enzymatically active reverse transcriptase in Escherichia coli

49. ExpressionPlot: a web-based framework for analysis of RNA-Seq and microarray gene expression data

50. From DNA to proteins via the ribosome: Structural insights into the workings of the translation machinery