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1. Directed Evolution of Protein Receptor Binding for Small Molecule Therapeutics Using Fluorescence Polarization

Bannier, Sean David
2021
Theses
ChemistryBiochemistryBiophysicsTetracylcinesProtein bindingPolarization (Light)Yeast

2. How to steal ribosomes: structural studies of two different internal ribosome entry sites

Neupane, Ritam
2021
Theses
BiochemistryBiophysicsVirologyRibosomesEukaryotic cellsCrickets

3. Structural and Biochemical Studies of the Human pre-mRNA 3’-end Processing Complex

Hamilton, Keith
2021
Theses
BiochemistryBiophysicsMessenger RNA--AnalysisMutagenesis

4. Investigation of Ribonuclease HI handle region dynamics using Solution-state nuclear magnetic resonance spectroscopy, Molecular Dynamic simulations and X-ray crystallography

Martin, James Arthur
2020
Theses
BiophysicsBiochemistryHIV (Viruses)Mouse leukemia virusesRNAEndonucleasesNuclear magnetic resonance spectroscopy

5. Structural and Biophysical Studies of Hair Cell Mechanotransduction Proteins

Dionne, Gilman
2020
Theses
BiochemistryBiophysicsProteinsCellular signal transduction--Research

6. The Critical Assessment of Protein Dynamics using Molecular Dynamics (MD) Simulations and Nuclear Magnetic Resonance (NMR) Spectroscopy Experimentation

Hsu, Andrew
2020
Theses
BiophysicsBiochemistryNuclear magnetic resonance spectroscopyMolecular dynamics--Computer simulation

7. Biomolecular NMR spectroscopy: Application to the study of the piRNA-pathway protein GTSF1, and backbone and side-chain spin relaxation methods development

O'Brien, Paul
2019
Theses
BiophysicsBiochemistryNuclear magnetic resonance spectroscopyProteins--StructureMolecular dynamics

8. Nucleosome Curtains and their application to the study of DNA condensation by condensin

Moevus, Corentin Jean
2019
Theses
BiochemistryBiophysicsDNACondensed matter

9. Solving Challenging Structures using Single-Particle Cryogenic Electron Microscopy

Tan, Yong Zi
2019
Theses
BiochemistryBiophysicsElectron microscopyMacromolecules--StructureRibosomesMembrane proteinsCytology--Technique

10. Using single molecule magnetic tweezers to dissect titin energy release during muscle contraction

Eckels, Edward Charles
2019
Theses
BiophysicsBiochemistryPhysiologyMagnetic tweezersMuscle contractionProtein folding

11. Allosteric Coupling, Nucleotide Binding and ATP Hydrolysis by Hsp70 Chaperones on a Structural Basis

Wang, Wei
2018
Theses
BiologyBiochemistryBiophysicsAllosteric regulationHeat shock proteins

12. Dynamic Nuclear Polarization with Biradical Affinity Reagents

Rogawski, Rivkah
2018
Theses
BiophysicsChemistryBiochemistryPolarization (Nuclear physics)Biradicals

13. Integration of EGFR and LIN-12/Notch signaling in Vulval Precursor Cell fate specification in Caenorhabditis elegans

Underwood, Ryan
2018
Theses
BiochemistryMetazoaCell interactionCellular signal transductionBiophysics

14. Structural and biophysical studies of the Drosophila melanogaster Dpr and DIP families

Cosmanescu, Filip
2018
Theses
BiochemistryNeurosciencesBiophysicsDrosophila melanogasterNeurons

15. Systematically Mapping the Epigenetic Context Dependence of Transcription Factor Binding

Kribelbauer, Judith Franziska
2018
Theses
BiochemistryBioinformaticsBiophysicsTranscription factorsGene regulatory networksEpigenetics

16. The Role of Eukaryotic Recombinase Loop L1 During Homologous Recombination

Steinfeld, Justin Benjamin
2018
Theses
BiophysicsBiochemistryGeneticsGenetic recombinationEukaryotic cells

17. The Saccharomyces cerevisiae Srs2 Helicase Regulates Homologous Recombination through the Disassembly of Recombination Intermediates

Kaniecki, Kyle Stephen
2018
Theses
GeneticsBiophysicsBiochemistrySaccharomyces cerevisiaeGenetic recombination

18. Cryo-electron microscopy and single particle reconstructions of the Leishmania major ribosome and of the encephalomyocarditis virus internal ribosome entry site bound to the 40S subunit

Jobe, Amy Beth
2017
Theses
Electron microscopyRibosomesLeishmaniaRNACryoelectronicsBiologyBiochemistryBiophysics

19. Nanoscale Electrical and Coarse-grained Molecular Dynamics Studies of Influenza Hemagglutinin-mediated Membrane Fusion Pores

Alcott, Brett Eugene
2017
Theses
BiophysicsBiochemistryVirologyMolecular dynamicsMembrane fusion

20. Regulation of Release Factor 2 in Non-canonical Translation Pathways

Huang, Bridget Yih Jiin
2017
Theses
Bacterial proteinsRibosomesBiochemistryProteins--SynthesisBiophysics