1. Characterization of pathogenic BicD2 mutations in vitro and in vivo. Yi, Julie Young Joo 2022 Theses CytologyMolecular biologyNeurosciencesMicrotubulesEukaryotic cellsDyneinMutagenesisKinesin
2. Noncoding translation mitigation Kesner, Jordan 2022 Theses Biology--ClassificationMolecular biologyCytologyEukaryotic cells--GeneticsAmino acid sequenceGenomesNucleotide sequenceRNA
3. Single-cell Analysis of Alopecia Areata Lee, Yoo Jin 2022 Theses ImmunologyMolecular biologyAlopecia areata--Animal modelsMiceBaldnessPathologyCytokinesLymphocytesNucleotide sequenceCancer--Treatment
4. The role of microRNA-219 in Alzheimer’s Disease-related tau proteostasis and pathology Cho, Joshua 2022 Theses Molecular biologyAlzheimer's disease--PathophysiologyNervous system--DiseasesDrosophila melanogasterMicePhosphorylation
5. A p53-independent role for MDM2-MDMX in cell cycle progression Klein, Alyssa Michelle 2021 Theses CytologyMolecular biologyBiochemistryCancerMutation
6. Leveraging the potential of human iPSC-derived cardiomyocytes: From modeling congenital heart disease to treating myocardial infarction Liu, Bohao 2021 Theses Biomedical engineeringMolecular biologyMedicineMyocardial infarctionCongenital heart diseaseHeart cellsStem cellsHuman beings
7. Phenotypic dissection and therapeutic manipulation of cell differentiation programs in the salivary gland epithelium and human Adenoid Cystic Carcinomas Viragova, Sara 2021 Theses CytologyMolecular biologySalivary glandsEpithelium--DiseasesAdenoid cystic carcinomaCancer--Radiotherapy
8. Pparg Drives Luminal Differentiation and Luminal Tumor Formation in the Urothelium Tate, Tiffany 2021 Theses OncologyCytologyMolecular biologyUrinary organsBladder--CancerBasal cell carcinoma
9. Spatially determined olfactory receptor choice is regulated by Nfi-dependent heterochromatin silencing and genomic compartmentalization Bashkirova, Elizaveta Vladimirovna 2021 Theses Molecular biologyHeterochromatinOlfactory receptorsOlfactory receptor genes
10. Structure and Function of a Transposon-Encoded CRISPR-Cas System Halpin-Healy, Tyler Sheehan 2021 Theses BiochemistryBiophysicsMolecular biologyVibrio choleraeRNADNA
11. Evolutionary and Functional Diversity of Regulatory Factors and Sequences that Coordinate Gene Expression Park, Jimin 2020 Theses Biology--ClassificationMolecular biologyMicrobiologyGenetic regulationGene expressionDNA--Synthesis
12. Generative Models for Synthetic Biology Blazejewski, Tomasz 2020 Theses BioinformaticsBiology--ClassificationMolecular biologySynthetic biologyMachine learningAmino acid sequence
13. Neuronal Topography in a Cortical Circuit for Innate Odor Valence Costantini, Daniel 2020 Theses NeurosciencesMolecular biologyOlfactory receptorsOdorsMiceNeurons
14. RNA mediated mechanisms of motor neuron death and dysfunction in SMA Van Alstyne, Meaghan 2020 Theses CytologyMolecular biologySpinal muscular atrophyMotor neuronsRNA
15. The FYN-TRAF3IP2 gene fusion drives oncogenic NF-κB signaling in peripheral T cell lymphoma Kim, Christine Sheila 2020 Theses Molecular biologyGeneticsOncologyHTLV (Viruses)CarcinogenesisGene fusion
16. The Role of N6-methyladenosine RNA Methylation in the Regulation of Hematopoietic Stem Cells Lee, Heather 2020 Theses CytologyMolecular biologyHematopoietic stem cellsDNA--MethylationCell differentiation
17. Understanding the Evolution of Recombination Rate Variation and PRDM9 Baker, Zachary 2020 Theses Biology--ClassificationEvolution (Biology)Molecular biologyMeiosisGenetic recombination
18. ER stress and lipid droplet-dependent proteostasis in response to lipid stress in yeast and a novel congenital muscular dystrophy Garcia, Enrique Jose 2019 Theses Molecular biologyCytologyLecithinMuscular dystrophyLipids
19. Function and tissue focus of daf-18/PTEN in maintaining blast cell multipotency and quiescence in Caenorhabditis elegans dauer larvae Tenen, Claudia 2019 Theses BiologyMultipotent stem cellsCaenorhabditis elegansMolecular biology
20. Liver X Receptor cis-Repression and Cholesterol Efflux Restrain Innate Immunity and Coronary Artery Disease Thomas, David George 2019 Theses CytologyMolecular biologyBiochemistryAtherosclerosis--PreventionImmunityNuclear receptors (Biochemistry)
21. Mechanisms and therapeutic targeting of NT5C2 mutations in relapsed acute lymphoblastic leukemia Dieck, Chelsea 2019 Theses BiochemistryLymphoblastic leukemiaDrug resistanceOncologyMutation (Biology)Molecular biology
22. Structural Analyses of the Transient Receptor Potential Channels TRPV3 and TRPV6 McGoldrick, Luke Lawrence Reedy 2019 Theses BiochemistryMolecular biologyTRP channelsStructure-activity relationships (Biochemistry)Ion channels
23. Abeta42 oligomers trigger synaptic loss through AMPK-dependent activation of mitochondrial fission and mitophagy Lee, Annie 2018 Theses CytologyNeurosciencesAlzheimer's disease--PathogenesisSynapsesMitochondriaOligomersMolecular biology
24. Analysis of Oncogenic Signal Transduction with Application to KRAS Signaling Pathways Broyde, Joshua 2018 Theses BioinformaticsBiometryMolecular biologyCancer--Molecular aspectsCellular signal transductionOncology
25. Asymmetric Cell Division in the Generation of Immunity and Tolerance Yen, Bonnie 2018 Theses ImmunologyCell divisionImmunological toleranceMolecular biology
26. Delineating the function, efficacy, and mechanism of a novel preclinical agent for the treatment of pancreatic ductal adenocarcinoma Eberle-Singh, Jaime 2018 Theses OncologyAdenocarcinomaPancreas--CancerCancer--TreatmentMedical sciencesMolecular biology
27. Identification and characterization of tissue-resident memory T cells in humans Kumar, Brahma Vencel 2018 Theses ImmunologyT cellsMedical sciencesMolecular biology
28. Investigations into pathophysiologic mechanisms and treatment of primary mitochondrial diseases Siegmund, Stephanie 2018 Theses Molecular biologyMitochondrial pathologyRapamycinBiology
29. Regulatory logic of cellular diversity in the nervous system Closser, Michael Edward 2018 Theses Molecular biologyNeurosciencesBioinformaticsNervous systemGene expressionCellular control mechanisms
30. The BARD1 BRCT Domain in Tumor Suppression and Genome Stability Billing, David 2018 Theses Molecular biologyCytologyBiochemistryTumor suppressor proteinsGenomes
31. Distinct Nuclear-Cytoskeletal LINCages Position the Nucleus for Homeostasis, Polarization and Migration Zhu, Ruijun 2017 Theses CytologyBiologyCell nucleiMolecular biology
32. Endothelial Caspase-9 Activity Exacerbates Edema and Neuronal Dysfunction after Retinal Vein Occlusion Avrutsky, Maria 2017 Theses CytologyEdemaRetina--Blood-vesselsMolecular biology
33. PTEN regulates glutamine flux to pyrimidine synthesis and sensitivity to dihydroorotate dehydrogenase inhibition Mathur, Deepti 2017 Theses Pyrimidines--SynthesisFibroblastsMice--EmbryosTumorsMetabolismGlutamine--MetabolismCytologyBiologyMolecular biologyOncology
34. Roles of transcription factor T-bet in memory CD4+ T cell generation, function, homeostasis and tissue targeting Chen, Jun Kui 2017 Theses ImmunologyT cells--DifferentiationTranscription factorsMolecular biology
35. Single-molecule observations of hRPA, RAD51, and RAD52 on single-stranded DNA Ma, Chu Jian 2017 Theses BiochemistryBiophysicsDNA replicationGenetic recombinationMolecular biology
36. Chloride Intracellular Channels 1 and 4 function in distinct branches of S1P signaling to regulate endothelial cell behavior and vascular development Jilishitz, Irina 2016 Theses MorphogenesisGrowth factorsNeovascularizationEndothelial cellsMolecular biologyBiochemistry
37. Dissecting the molecular basis of PfCRT-mediated antimalarial drug resistance Gabryszewski, Stanislaw J. 2016 Theses Drug resistanceChloroquineMedical sciencesPlasmodium falciparumMicrobiologyMolecular biologyParasitology
38. Analysis of Ureteric Bud Morphogenesis by Reassociation of Fetal Kidney Cells Leclerc, Kevin 2015 Theses KidneysMetalloproteinasesExtracellular matrixMorphogenesis--Molecular aspectsGeneticsMolecular biology
39. A Targetable GATA2-IGF2 Axis Confers Aggressiveness in Chemotherapy Resistant Prostate Cancer Vidal, Samuel J. 2015 Theses Molecular biologyOncology
40. Characterizing the Mechanism of Tumor Suppression by PBRM1 in Clear Cell Renal Cell Carcinoma Schoenfeld, David Aaron 2015 Theses Renal cell carcinomaCancer--Genetic aspectsCarcinogenesisOncogenesAntioncogenesMolecular biologyOncology
41. Investigating the role of the RNA binding protein TDP-43 in Amyotrophic Lateral Sclerosis using animal and cell-based models of disease Lehrer, Helaina 2015 Theses Molecular biologyNeurosciencesBiochemistry
42. Notch signaling regulates myeloid cell function and contribution to angiogenesis Tattersall, Ian William 2015 Theses CytologyImmunologyMolecular biology
43. Reprogramming protein synthesis for cell engineering Anzalone, Andrew Vito 2015 Theses Proteins--SynthesisBioengineeringAmino acids--BiotechnologyRNA-protein interactionsSynthetic biologyBiochemistryChemistry, OrganicBiologyMolecular biology
44. RNA-Dependent Control of Histone Gene Expression by the Spinal Muscular Atrophy Protein SMN: Mechanisms and Role in Motor Neuron Disease Tisdale, Sarah 2015 Theses Gene expressionGenetic regulationProteins--SynthesisBiosynthesisMotor neuronsNucleoproteinsMolecular biologyCytologyNeurosciences
45. Therapeutic targeting of Hairy and Enhancer of Split 1 (HES1) transcriptional programs in T-cell Acute Lymphoblastic Leukemia Schnell, Stephanie A. 2015 Theses MedicineMolecular biologyImmunology
46. The Roles of F-box and Leucine-Rich Repeat Protein 4 (FBXL4) in Mitochondrial Encephalopathy and T-cell Acute Lymphoblastic Leukemia Haydu, Julie Erika M. 2015 Theses Mitochondrial pathologyGeneticsMolecular biologyMedicine
47. Transcriptional States and microRNA Regulation of Adult Neural Stem Cells DeLeo, Annina 2015 Theses Molecular biologyNeurosciencesBioinformatics
48. Understanding mechanisms of beta cell susceptibility to type 1 diabetes Kim, YoungJung 2015 Theses InflammationPancreatic beta cellsDiabetesMolecular biologyMedicine
49. Dissecting the non-canonical functions of p53 through novel target identification and p53 acetylation Wang, Shang-Jui 2014 Theses CytologyMolecular biologyAcetylationp53 antioncogeneMice--Genetics
50. Macroautophagy Modulates Synaptic Function in the Striatum Torres, Ciara 2014 Theses RapamycinProteinsCorpus striatumCytologyMolecular biologyPsychology