1. UVSSA regulates transcription-coupled genome maintenance Liebau, Rowyn Church 2024 Theses Molecular biologyDNA damageDNA repairDNA replicationScaffold proteinsGenomesGenetic transcription--RegulationCancer--Genetic aspects
2. A Computational Approach to Rational Engineering of Protein Crystallization Banayan, Nooriel Elan 2023 Theses BiophysicsX-ray crystallographyCrystalloids (Botany)CrystallizationArginineLysine
3. A transcriptomic taxonomy of human microglia: Uncovering roles and regulators in aging and neurologic disease. Tuddenham, John Francis 2023 Theses NeurosciencesMicrogliaNervous system--Diseases--TreatmentCamptothecinAmyotrophic lateral sclerosisNucleotide sequence
4. Cellular arrangement in Pseudomonas aeruginosa biofilms Dayton, Hannah Teckla 2023 Theses BiologyPseudomonas aeruginosaBiofilmsDrug resistance in microorganisms
5. Comparative analysis of nuclear proteomes and strain-specific chromosomes in Oxytricha trifallax Lu, Michael 2023 Theses BiologyCiliata--GeneticsGenomesProteomicsChromosomes
6. Discovery and Optimization of Novel Small-Molecule Inhibitors of Glutathione Peroxidase 4 Lin, Annie 2023 Theses BiologyDrug resistance in cancer cellsCell deathGlutathioneCancer cells--Effect of drugs on
7. Exploring a non-canonical mode of gene regulation mediated by mRNA transcript isoform switching in the context of mammalian development Keskin, Abdurrahman 2023 Theses BiologyEmbryonic stem cellsGene expressionMammals--GeneticsMammals--Development
8. Functional specification of the Caenorhabditis elegans nervous system by homeodomain transcription factors Cros, Cyril Christophe 2023 Theses Developmental biologyNeurosciencesCaenorhabditis elegansNervous systemNeurons
9. Genetic Variant Effects on Transcription Factor Regulation Li, Xiaoting 2023 Theses BiologyHuman genetics--VariationDiseases--Risk factorsHuman genomeGenomicsGenetic transcriptionGene expression
10. Homology-Directed Repair of One- and Two-Ended DNA Double-Strand Breaks Kimble, Michael Taylor 2023 Theses GeneticsDouble-stranded RNADNA repairGenomesDNA damageYeast--GeneticsGenetic recombination
11. Non-canonical WDR33 Isoforms: Characterization, Regulation, and Functional Significances in STING-Mediated Innate Immune Responses Liu, Lizhi 2023 Theses Molecular biologyImmunologyBiochemistryAmino acid sequenceGene expressionMessenger RNAOligomerizationInterferon
12. Population genetic models of mutation rate evolution and adaptation and the impact of essential workers in the context of social distancing for epidemic control Milligan, William Robert 2023 Theses BiologyEvolution (Biology)MutagenesisGerm cellsSocial distancing (Public health)Epidemics--PreventionEpidemiologyAllelomorphismIndustrial hygiene
13. Regulation of EGFR signal transduction and cell division in quiescent Vulval Precursor Cells during dauer developmental arrest O'Keeffe, Catherine 2023 Theses BiologyDevelopmental biologyCaenorhabditis elegansStem cellsVulvaCell division
14. Regulation of redox metabolism in Pseudomonas aeruginosa biofilms Smiley, Marina K. 2023 Theses MicrobiologyBiologyPseudomonas aeruginosaBiofilmsBacteriaDenitrificationPhenazineAnti-infective agents
15. Spatially resolved molecular dysfunction in the prefrontal cortex of patients with amyotrophic lateral sclerosis (ALS) Petrescu, Joana 2023 Theses NeurosciencesAmyotrophic lateral sclerosisNervous system--DiseasesFrontotemporal dementiaPrefrontal cortex
16. SPIDR: The development and application of a highly multiplexed CLIP-seq method Wolin, Erica 2023 Theses Molecular biologyRNA-protein interactionsRNA--Analysis
17. Structural and Functional Studies of CNG channels Hu, Zhengshan 2023 Theses BiologyBiochemistryBiophysicsCyclic nucleotides--AnalysisIon channelsCryoelectronicsElectron microscopy
18. Studies on Eukaryotic Pre-mRNA 3'-End Processing: Insights into PAS Recognition and the U7 snRNP activity Gutierrez Tamayo, Pedro A. 2023 Theses BiologyBiochemical geneticsBiophysicsEukaryotic cells--GeneticsMessenger RNAVertebratesMammals--Molecular genetics
19. The Role of Kinesins in Cell Fate Determination During Neurogenesis Helmer, Paige 2023 Theses BiologyKinesinNeurogeneticsNeuronsBrain--PhysiologyMammals--Nervous systemNeuroglia
20. The Role of the Tail of the Striatum in Associative Learning Stanley, Adrien Trejo 2023 Theses NeurosciencesPaired-association learningMiceBasal gangliaSerotoninNoradrenaline
21. The Role of the Type VI Secretion System in the Adaptation of Pseudomonas aeruginosa to the Lung Fields, Blanche L. 2023 Theses MicrobiologyImmunologyPseudomonas aeruginosa infectionsCystic fibrosis--PatientsLungs--InfectionsProteins--Secretion
22. Understanding the molecular, cellular, and circuit defects characterizing the early stages of Alzheimer’s disease Virga, Daniel Michael 2023 Theses NeurosciencesAlzheimer's disease--PathophysiologyAlzheimer's disease--EtiologyCytologyMolecular biologyNervous system--DiseasesHippocampus (Brain)SynapsesDendritesMitochondrial pathology
23. Widespread 3D genome reorganization precedes programmed DNA rearrangement in Oxytricha trifallax Villano, Danylo Julian 2023 Theses BiologyMolecular biologyGeneticsGenomesCiliataRNAGene rearrangement
24. A genetically-encoded biosensor and a conditional gene expression system for investigating Notch activity in vivo Shaffer, Justin Matthew 2022 Theses Developmental biologyGeneticsGene expressionCell interactionCaenorhabditis elegans--GeneticsExons (Genetics)
25. Analysis of Conformational Continuum and Free-energy Landscapes from Manifold Embedding of Single-particle Cryo-EM Ensembles of Biomolecules Seitz, Evan Elliott 2022 Theses Molecular biologyBiomoleculesElectron microscopy—Data processingMachine learningRiemannian manifoldsGibbs' free energyPath analysis (Statistics)RibosomesCOVID-19 (Disease)--Data processing
26. A non-canonical Hippo signaling pathway regulates DeltaNp63 in cancer cells Low Calle, Ana Maria 2022 Theses Molecular biologySquamous cell carcinomaTranscription factors
27. Auditory Tuning in Vocal Learning Songbirds Yeh, Yow-Tyng 2022 Theses BiologyNeurosciencesSongbirdsBirds--VocalizationBirdsongsSensorimotor cortex
28. Cardiomyopathy at the Intersection of Stem Cells and Tissue Engineering Wang, Bryan Zicheng 2022 Theses BiologyMyocardium--DiseasesStem cellsGene editingTissue engineeringHeart--Diseases--Genetic aspects
29. Detection of respiratory gas levels by internal sensory neurons in Drosophila larvae Lu, Shan 2022 Theses NeurosciencesDrosophila--DevelopmentSensory neuronsHypoxia (Water)Carbon dioxideRespiratory gas monitoringInsects--Larvae
30. Development of genetically intact bioengineered spores of Bacillus subtilis Flores Quijano, Juan Manuel de Jesus 2022 Theses BiologyBacillus subtilis--GeneticsPlasmids--GeneticsBiotechnologyNatural pesticidesProbiotics
31. Expression and Functional Analyses of the Entire Cadherin Gene Family in C. elegans Majeed, Maryam 2022 Theses BiologyNeurosciencesCaenorhabditis elegans--GeneticsGene expressionCadherins
32. Multidimensional encoding of context in auditory cortex Shymkiv, Yuriy 2022 Theses NeurosciencesAuditory cortexCalcium imagingSensory stimulation
33. Nucleolar transcription and its connections to nucleolar homeostasis and mitochondrial stress responses Feng, Shuang 2022 Theses Molecular biologyNucleic acidsHomeostasisMitochondriaCarcinogenesisNervous system--Diseases
34. Production and properties of the Pseudomonas aeruginosa R-body virulence factor Wang, Bryan 2022 Theses MicrobiologyPseudomonas aeruginosaAntibiotics--Therapeutic useBiofilms
35. Real-time observation of vitamin B12 transport by BtuCD-F at the single-molecule level Zhu, Lingwei 2022 Theses BiophysicsHydrolysisVitamin B12ATP-binding cassette transporters
36. Studies of Caenorhabditis elegans neuronal cell fate Tekieli, Tessa 2022 Theses NeurobiologyCaenorhabditis elegansCaenorhabditis elegans--GeneticsNervous systemDopaminergic neuronsHomeobox genes
37. The role of Distal antenna in the regulation of D. melanogaster neural stem cell competence Benchorin, Gillie 2022 Theses Developmental biologyNeurosciencesCytologyDrosophila melanogasterDrosophila melanogaster--PhysiologyGenomesDNA-binding proteinsNuclear proteinsAntennae (Biology)
38. Understanding and Engineering Multicomponent Living Systems: Examples from Synthetic Genomics and Engineered Living Materials McBee, Andrew Ross MacKay 2022 Theses BiologySynthetic biologyGenomicsMetazoaAmino acidsValineMycelium
39. A Comparative Analysis of Genome Rearrangement in Ciliates Feng, Yi 2021 Theses BiologyBioinformaticsEvolution (Biology)Gene rearrangementCiliata--GeneticsEuplotesGenetic code
40. Broad-scale variation in human genetic diversity levels is predicted by purifying selection on coding and non-coding elements Murphy, David 2021 Theses GeneticsEvolution (Biology)BiologyHuman genomeBiodiversity
41. Characterizing molecular drivers of clinical outcome in pediatric acute leukemias by systems biology and machine learning Alloy, Alexandre Paul 2021 Theses BioinformaticsLeukemia--Genetic aspectsLeukemia in childrenMachine learningAcute leukemia
42. Disentangling mutation and selection in human genetic variation: promises and pitfalls Agarwal, Ipsita 2021 Theses BiologyGeneticsEvolution (Biology)Mutation (Biology)Human genomeExomes
43. Effects of antidepressants on the ventral dentate gyrus Carazo Arias, Elena 2021 Theses NeurosciencesFluoxetineDentate gyrusAntidepressants--Physiological effect
44. Electromechanical Coupling in Cells and Its Effects on Membrane Tension and Conductance Jones Molina, John Anthony 2021 Theses BiophysicsCytologyBiologyCell membranes
45. Framework for Mapping Gene Regulation via Single-cell Genetic Screens Tan, Xiangtian 2021 Theses BiologyCytologyGenetic transcription--RegulationCancer cellsProteins--Analysis
46. Function and Regulation of ALS/FTD-associated RNA Binding Protein FUS Tsai, Yueh-Lin 2021 Theses BiologyCytologyMolecular biologyRNA-protein interactionsAmyotrophic lateral sclerosisDementia
47. How to steal ribosomes: structural studies of two different internal ribosome entry sites Neupane, Ritam 2021 Theses BiochemistryBiophysicsVirologyRibosomesEukaryotic cells
48. Investigations into a bHLH code for Caenorhabditis elegans somatic gonad regulatory cell fate and function Littleford, Hana Elisabeth 2021 Theses Developmental biologyGeneticsCaenorhabditis elegans--GeneticsGenetic regulation
49. Learning in Multi-Layer Networks of the Brain Muller, Salomon 2021 Theses NeurosciencesNeural circuitryHippocampus (Brain)MormyridaeVestibulo-ocular reflexCerebellar cortex
50. Mutagenic Repair Outcomes of DNA Double-Strand Breaks Al-Zain, Amr M. 2021 Theses BiologyMolecular biologyDouble-stranded RNACancer--EtiologyCancer--Genetic aspectsGenomesMutagenesis