1. Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models Mendioroz, Maite; Do, Catherine; Jiang, Xiaoling; Liu, Chunhong; Darbary, Huferesh; Lang, Charles F.; Lin, John; Thomas, Anna; Abu-Amero, Sayeda; Stanier, Philip; Temkin, Alexis; Yale, Alexander; Liu, Meng-Min; Li, Yang; Salas, Martha C.; Kerkel, Kristi; Capone, George; Silverman, Wayne; Yu, Y. Eugene; Moore, Gudrun; Wegiel, Jerzy; Tycko, Benjamin 2015 Articles EpigeneticsChromosomesDown syndromeGeneticsBiomechanics
2. Creation and characterization of BAC-transgenic mice with physiological over-expression of epitope-tagged RCAN1 (DSCR1) Xing, Luzhou; Salas, Martha; Zhang, Hong; Gittler, Julia; Ludwig, Thomas; Lin, Chyuan-Sheng; Vundavalli, Murty V.; Silverman, Wayne; Arancio, Ottavio; Tycko, Benjamin 2013 Articles GenomicsGeneticsHuman chromosome 21Down syndrome--Genetic aspectsTransgenic mice
3. Altered DNA Methylation in Leukocytes with Trisomy 21 Kerkel, Kristi; Schupf, Nicole; Hatta, Kota; Pang, Deborah I.; Salas, Martha; Kratz, Alexander; Minden, Mark; Vundavalli, Murty V.; Zigman, Warren; Mayeux, Richard Paul; Jenkins, Edmund C.; Torkamani, Ali; Schork, Nicholas J.; Silverman, Wayne; Croy, B. Anne; Tycko, Benjamin 2010 Articles DNA--MethylationT cellsDown syndromeAutoimmune diseasesGenetics
4. Faithful tissue-specific expression of the human chromosome 21-linked COL6A1 gene in BAC-transgenic mice Xing, Luzhou; Salas, Martha; Lin, Chyuan-Sheng; Zigman, Warren; Silverman, Wayne; Subramaniyam, Shivakumar; Vundavalli, Murty V.; Tycko, Benjamin 2007 Articles Gene expressionDown syndromeEndocardial cushion defectsBacterial artificial chromosomes
5. Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21 Li, Chi-Ming; Guo, Meirong; Salas, Martha; Schupf, Nicole; Silverman, Wayne; Zigman, Warren; Husain, Sameera; Warburton, Dorothy P.; Thaker, Harshwardhan; Tycko, Benjamin 2006 Articles Gene expressionDown syndromeGeneticsCytology
6. Obesity enhances verbal memory in postmenopausal women with Down syndrome Patel, Bindu N.; Pang, Deborah; Stern, Yaakov; Silverman, Wayne; Kline, Jennie K.; Mayeux, Richard; Schupf, Nicole 2004 Articles NeurologyCognition
7. Onset of dementia is associated with age at menopause in women with Down's syndrome Schupf, Nicole; Pang, Deborah; Patel, Bindu N.; Silverman, Wayne; Schubert, Romaine; Lai, Florence; Kline, Jennie K.; Stern, Yaakov; Ferin, Michel; Tycko, Benjamin; Mayeux, Richard 2003 Articles NeurologyCognition