2014 Articles

Cerebral microbleeds in a multiethnic elderly community: Demographic and clinical correlates

Wiegman, Anne F.; Meier, Irene B.; Schupf, Nicole; Manly, Jennifer J.; Guzman, Vanessa A.; Narkhede, Atul; Stern, Yaakov; Martinez-Ramirez, Sergi; Viswanathan, Anand; Luchsinger, José A.; Greenberg, Steven M.; Mayeux, Richard; Brickman, Adam M.

Background—Microbleeds, small perivascular collections of hemosiderin manifested radiologically as hypointensities on gradient-echo magnetic resonance imaging (MRI), are important markers of small vessel pathology. Despite their clinical relevance, little is known about their prevalence and demographic correlates, particularly among ethnically diverse older adults. We examined demographic and clinical correlates of regional microbleeds in a multi-ethnic cohort and examined categorization schemes of microbleed distribution and severity.