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Association of Researcher Characteristics with Views on Return of Incidental Findings from Genomic Research

Wynn, Julia; Martinez, Josue Natanael; Duong, Jimmy; Zhang, Yuan; Phelan, Jo C.; Fyer, Abby; Klitzman, Robert L.; Appelbaum, Paul S.; Chung, Wendy K.

Whole exome/ genome sequencing (WES/WGS) is now commonly used in research and is increasingly used in clinical care to identify the genetic basis of rare and unknown diseases. The management of incidental findings (IFs) generated through these analyses is debated within the research community. To examine how views regarding genomic research IFs are associated with researcher characteristics and experiences, we surveyed genetic professionals and assessed the effect of professional background and experience on their opinions. Researchers who did not have clinical training, provide clinical care to research participants, or have prior experience returning research results were in general more inclined to offer return of IFs than their colleagues with these characteristics. Understanding this will be important to fully appreciate the impact that policies on return of genetic IFs could have on participants, researchers, and genomic research.

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Also Published In

Title
Journal of Genetic Counseling
DOI
https://doi.org/10.1007/s10897-014-9817-1

More About This Work

Academic Units
Biostatistics
Pediatrics
Psychiatry
Sociomedical Sciences
Published Here
July 15, 2020