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History of periodontal treatment and risk for intrauterine growth restriction (IUGR)

Ananth, Cande V.; Andrews, Howard F.; Papapanou, Panos N.; Ward, Angela M.; Bruzelius, Emilie; Conicella, Mary L.; Albert, David A.

Background
To explore the hypothesis that maternal periodontitis is associated with increased risk for Intrauterine Growth Restriction (IUGR), we examined the risk of IUGR in relation to periodontal treatment before, during and after pregnancy.

Methods
We conducted a retrospective cohort analysis of insurance claims data from 2009 to 2012 for women who delivered a singleton live birth (n = 32,168). IUGR was examined as a function of type and timing of dental treatment, adjusting for potential confounders in logistic regression. Sensitivity analysis evaluated the potential effects of unmeasured confounding.

Results
Women who received periodontal treatment after delivery, indicating the presence of untreated periodontal disease during pregnancy, had significantly higher odds of IUGR compared to women who received no periodontal treatment (adjusted OR 1.5, 95% CI 1.2, 1.8).

Conclusions
Periodontal treatment provided in the immediate postpartum period, a proxy for periodontitis during gestation, was associated with increased risk of IUGR.

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Also Published In

Title
BMC Oral Health
DOI
https://doi.org/10.1186/s12903-018-0623-2

More About This Work

Academic Units
Obstetrics and Gynecology
Epidemiology
Biostatistics
Dental Medicine
Published Here
March 8, 2019

Notes

Periodontal treatment, Fetal inflammatory response, Intrauterine growth restriction

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