2018 Articles

Emerging concepts and challenges in implementing the exposome paradigm in allergic diseases and asthma.

Agache, Ioana; Miller, Rachel L.; Gern, James E.; Hellings, Peter W.; Jutel, Marek; Muraro, Antonella; Phipatanakul, Wanda; Quirce, Santiago; Peden, David

Exposome research can improve the understanding of the mechanistic connections between exposures and health to help mitigate adverse health outcomes across the life span. The exposomic approach provides a risk profile instead of single predictors and thus is particularly applicable to allergic diseases and asthma. Under the PRACTALL collaboration between the European Academy of Allergy and Clinical Immunology (EAACI) and the American Academy of Allergy, Asthma, and Immunology (AAAAI), we evaluated the current concepts and the unmet needs on the role of the exposome in allergic diseases and asthma.