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Controversies concerning mitochondrial replacement therapy

Klitzman, Robert L.; Toynbee, Mark; Sauer, Mark V.

Research on mitochondrial replacement therapy (MRT) holds the promise of helping women who have, or are at risk of transmitting, mitochondrial disease, but has recently been blocked by the Food and Drug Administration (FDA). Thus, several critical ethical and policy questions arise. Mitochondrial disease can be devastating for those who have it. Yet existing treatments remain supportive rather than curative. Women confronting this disease have a high chance of having an affected child and limited reproductive alternatives.

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Also Published In

Title
Fertility and Sterility
DOI
https://doi.org/10.1016/j.fertnstert.2014.10.028

More About This Work

Academic Units
Obstetrics and Gynecology
Psychiatry
Published Here
July 20, 2020