Academic Commons

Articles

Local Knowledge and Single IRBs for Multisite Studies: Challenges and Solutions

Klitzman, Robert L.; Pivovarova, Ekaterina; Murray, Alexandra; Appelbaum, Paul S.; Stiles, Deborah F.; Lidz, Charles W.

New federal policies require single IRB review for multisite studies, but many questions remain about how these IRBs will use local knowledge. The findings from our study, the first to examine how single IRBs perceive needs for local knowledge, reveal several challenges. Study respondents identified four potentially relevant types of local knowledge: about culture and linguistics, about geography and socioeconomics, about the researchers, and about the institutions. Such knowledge can potentially be obtained through local sites, but single IRBs may be unaware of potentially relevant local information, and lack of informal relationships may impede single IRBs’ reviews and interactions with researchers. While a recent, commonly used, standardized single‐IRB form asks three basic questions about local information, our findings suggest potential needs for additional information and, thus, have important implications for practice, policy, and research.

Files

  • thumnail for Klitzman_Local Knowledge and Single IRBs for Multisite Studies_Challenges and Solutions.pdf Klitzman_Local Knowledge and Single IRBs for Multisite Studies_Challenges and Solutions.pdf application/pdf 191 KB Download File

Also Published In

Title
Ethics & Human Research
DOI
https://doi.org/10.1002/eahr.500003

More About This Work

Academic Units
Office of the Executive Vice President for Research
Psychiatry
Published Here
July 24, 2020