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Unbalanced t(2;19) and t(2;16) in a neurofibroma

Nandula, Subhadra; Borczuk, Alain C.; Vundavalli, Murty V.

Neurofibromas are a benign heterogeneous group of tumors arising from peripheral nerve sheaths; they consist of a mixture of Schwann cells, fibroblasts, perineural cells, neuronal processes, and mast cells. Neurofibromas may present as dermal (cutaneous or subcutaneous) or plexiform (diffuse growths, spinal tumors, nodular or diffuse) tumors. They may present as isolated sporadic tumors in the general population or occur as a part of an autosomal dominant tumor diathesis in von Recklinghausen neurofibromatosis type 1 (NF1).

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Title
Cancer Genetics and Cytogenetics
DOI
https://doi.org/10.1016/j.cancergencyto.2003.12.005

More About This Work

Academic Units
Pathology and Cell Biology
Published Here
February 7, 2020