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Novel Borna virus in psittacine birds with proventricular dilatation disease

Honkavuori, Kirsi S.; Shivaprasad, H. L.; Williams, Brent L.; Quan, Phuong-Lan; Hornig, Mady; Street, Craig; Palacios, Gustavo F.; Hutchison, Stephen K.; Franca, Monique; Briese, Thomas; Lipkin, W. Ian; Egholm, Michael

Pyrosequencing of cDNA from brains of parrots with proventricular dilatation disease (PDD), an unexplained fatal inflammatory central, autonomic, and peripheral nervous system disease, showed 2 strains of a novel Borna virus. Real-time PCR confirmed virus presence in brain, proventriculus, and adrenal gland of 3 birds with PDD but not in 4 unaffected birds.

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Title
Emerging Infectious Diseases
DOI
https://doi.org/10.3201/eid1412.080984

More About This Work

Academic Units
Center for Infection and Immunity
Published Here
March 11, 2011