2013 Articles
Characterization of Farmington virus, a novel virus from birds that is distantly related to members of the family Rhabdoviridae
Background: Farmington virus (FARV) is a rhabdovirus that was isolated from a wild bird during an outbreak of epizootic eastern equine encephalitis on a pheasant farm in Connecticut, USA. Findings: Analysis of the nearly complete genome sequence of the prototype CT AN 114 strain indicates that it encodes the five canonical rhabdovirus structural proteins (N, P, M, G and L) with alternative ORFs (> 180 nt) in the N and G genes. Phenotypic and genetic characterization of FARV has confirmed that it is a novel rhabdovirus and probably represents a new species within the family Rhabdoviridae. Conclusions: In sum, our analysis indicates that FARV represents a new species within the family Rhabdoviridae.
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Also Published In
- Title
- Virology Journal
- DOI
- https://doi.org/10.1186/1743-422X-10-219
More About This Work
- Academic Units
- Center for Infection and Immunity
- Published Here
- September 9, 2014
Notes
Farmington virus (FARV), Family Rhabdoviridae, Next generation sequencing, Phylogeny