2014 Articles
Focal Task-specific Dystonia—From Early Descriptions to a New, Modern Formulation
Background: Vivid descriptions of the phenomenology of focal task‐specific dystonia (FTSD) date back to the late nineteenth century.
Methods: In this review, I summarize the natural history, phenomenology, and treatment of FTSD, focusing on nineteenth‐century neurologists' descriptions of the phenomenology, etiology, treatment, and mechanism.
Results: Examining these texts through a twenty‐first‐century lens, the “modern” ideas of a dystonic endophenotype, disordered physiology, and dystonic metabolic networks actually appeared in these texts more than a century ago.
Discussion: By incorporating these ideas with recent investigations, I present a new conceptual model for understanding this mysterious malady.
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Also Published In
- Title
- Tremor and Other Hyperkinetic Movements
- DOI
- https://doi.org/10.7916/D8VD6WHP
More About This Work
- Academic Units
- Center for Parkinson's Disease and Other Movement Disorders
- Published Here
- November 2, 2014