Focal Task-specific Dystonia—From Early Descriptions to a New, Modern Formulation

Frucht, Steven J.

Background: Vivid descriptions of the phenomenology of focal task‐specific dystonia (FTSD) date back to the late nineteenth century.

Methods: In this review, I summarize the natural history, phenomenology, and treatment of FTSD, focusing on nineteenth‐century neurologists' descriptions of the phenomenology, etiology, treatment, and mechanism.

Results: Examining these texts through a twenty‐first‐century lens, the “modern” ideas of a dystonic endophenotype, disordered physiology, and dystonic metabolic networks actually appeared in these texts more than a century ago.

Discussion: By incorporating these ideas with recent investigations, I present a new conceptual model for understanding this mysterious malady.



Also Published In

Tremor and Other Hyperkinetic Movements

More About This Work

Academic Units
Center for Parkinson's Disease and Other Movement Disorders
Published Here
November 2, 2014