Nosocomial outbreak of novel arenavirus infection, Southern Africa

Paweska, Janusz T.; Sewlall, Nivesh H.; Ksiazek, Thomas G.; Blumberg, Lucille H.; Hale, Martin J.; Lipkin, W. Ian; Weyer, Jacqueline; Nichol, Stuart T.; Rollin, Pierre E.; McMullan, Laura K.; Paddock, Christopher D.; Briese, Thomas; Mnyaluza, Joy; Dinh, Thu-Ha; Mukonka, Victor; Ching, Pamela; Duse, Adriano; Richards, Guy; De Jong, Gillian; Cohen, Cheryl; Ikalafeng, Bridget; Mugero, Charles; Asomugha, Chika; Malotle, Mirriam M.; Nteo, Dorothy M.; Misiani, Eunice; Swanepoel, Robert; Zaki, Sherif R.

A nosocomial outbreak of disease involving 5 patients, 4 of whom died, occurred in South Africa during September—October 2008. The first patient had been transferred from Zambia to South Africa for medical management. Three cases involved secondary spread of infection from the first patient, and 1 was a tertiary infection. A novel arenavirus was identified. The source of the first patient's infection remains undetermined.

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Emerging Infectious Diseases

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Center for Infection and Immunity
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March 11, 2011