High Voltage VIM Region Deep Brain Stimulation Mimicking Progressive Supranuclear Palsy

Patterson, Addie; Okun, Michael S.; Hess, Christopher W.

Background: Deep brain stimulation (DBS) for essential tremor (ET) can cause unwanted side effects.

Case Report: A patient with ET underwent unilateral dual-lead thalamic DBS. He later developed parkinsonism with atypical features and was diagnosed with progressive supranuclear palsy. During presentation for a second opinion, stimulation-induced side effects were suspected. Inactivation of DBS resolved atypical features and superimposed idiopathic Parkinson Disease (PD) was diagnosed.

Discussion: This case illustrates the importance of recognizing the possible influence of stimulation-induced side effects and discusses when to utilize dual-lead DBS for ET and the co-occurrence of ET and PD.


Also Published In

Tremor and Other Hyperkinetic Movements

More About This Work

Academic Units
Center for Parkinson's Disease and Other Movement Disorders
Published Here
November 22, 2017