2011 Abstracts (Summaries)
MicroRNA expression in HTLV-1 infection and pathogenesis
Our laboratory is examining the profiles of microRNA expression in ATLL cells and infected T-cell lines using microarrays and small RNA libraries.
Microarray analysis of ATLL samples revealed 6 upregulated and 21 downregulated microRNAs in ATLL cells compared to CD4+ T-cell controls. Potential targets for deregulated microRNAs were identified by integrating microRNA and mRNA expression profiles. Current experiments are aimed at verifying these predicted microRNA-target interactions.
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More About This Work
- Academic Units
- Pathology and Cell Biology
- BioMed Central
- Published Here
- September 9, 2014