2013 Articles
A Reliable Way to Detect Endogenous Murine β-Amyloid
Unraveling the normal physiologic role of β-amyloid is likely crucial to understanding the pathogenesis of Alzheimer's disease. However, progress on this question is currently limited by the high background of many ELISAs for murine β-amyloid. Here, we examine the background signal of several murine β-amyloid ELISAs, and conclude that the majority of the background is from non-APP derived proteins. Most importantly, we identify ELISAs that eliminate this background signal.
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pone.0055647.pdf application/pdf 550 KB Download File
Also Published In
- Title
- PLOS One
- DOI
- https://doi.org/10.1371/journal.pone.0055647
More About This Work
- Academic Units
- Pathology and Cell Biology
- Published Here
- May 8, 2013