Academic Commons

Articles

Results of soy-based meal replacement formula on weight, anthropometry, serum lipids and blood pressure during a 40-week clinical weight loss trial

Fontaine, Kevin; Yang, Dongyan; Gadbury, Gary; Heshka, Stanley; Schwartz, Linda; Murugesan, Radha; Kraker, Jennifer; Heo, Moonseong; Heymsfield, Steven B.; Allison, David

To evaluate the intermediate-term health outcomes associated with a soy-based meal replacement, and to compare the weight loss efficacy of two distinct patterns of caloric restriction. Ninety overweight/obese (28 < BMI ≤ 41 kg/m2) adults received a single session of dietary counseling and were randomized to either 12 weeks at 1200 kcal/day, 16 weeks at 1500 kcal/d and 12 weeks at 1800 kcal/d (i.e., the 12/15/18 diet group), or 28 weeks at 1500 kcal/d and 12 weeks at 1800 kcal/d (i.e., the 15/18 diet group). Weight, body fat, waist circumference, blood pressure and serum lipid concentrations were measured at 4-week intervals throughout the 40-week trial. Subjects in both treatments showed statistically significant improvements in outcomes. A regression model for weight change suggests that subjects with larger baseline weights tended to lose more weight and subjects in the 12/15/18 group tended to experience, on average, an additional 0.9 kg of weight loss compared with subjects in the 15/18 group. Both treatments using the soy-based meal replacement program were associated with significant and comparable weight loss and improvements on selected health variables.

Subjects

Files

  • thumnail for 305e1ff65fbc01f6604910ac64b43311.zip 305e1ff65fbc01f6604910ac64b43311.zip binary/octet-stream 223 KB Download File

Also Published In

Title
Nutrition Journal
DOI
https://doi.org/10.1186/1475-2891-2-14

More About This Work

Academic Units
Institute of Human Nutrition
Surgery
Publisher
BioMed Central
Published Here
September 8, 2014
Academic Commons provides global access to research and scholarship produced at Columbia University, Barnard College, Teachers College, Union Theological Seminary and Jewish Theological Seminary. Academic Commons is managed by the Columbia University Libraries.