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A note on QTL detecting for censored traits

Fang, Yixin

Most existing statistical methods for mapping quantitative trait loci (QTL) assume that the phenotype follows a normal distribution and that it is fully observed. However, some phenotypes have skewed distributions and may be censored. This note proposes a simple and efficient approach to QTL detecting for censored traits with the Cox PH model without estimating the baseline hazard function which is "nuisance".


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Also Published In

Genetics Selection Evolution

More About This Work

Academic Units
BioMed Central
Published Here
September 9, 2014


QTL detecting, censored trait, interval mapping

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