HIV-Selectest Enzyme Immunoassay and Rapid Test: Ability to Detect Seroconversion following HIV-1 Infection

Khurana, Surender; Norris, Philip J.; Busch, Michael P.; Haynes, Barton F.; Park, Susan; Sasono, Pretty; Mlisana, Koleka P.; Abdool Karim, Salim; Hecht, Frederick M.; Mulenga, Joseph; Chomba, Elwyn; Hunter, Eric; Allen, Susan; Nemo, George; Rodriguez-Chavez, Isaac R.; Margolick, Joseph B.; Golding, Hana

HIV-Selectest is a serodiagnostic enzyme immunoassay (EIA), containing p6 and gp41 peptides, designed to differentiate between vaccine-induced antibodies and true infections. A rapid test version of the HIV-Selectest was developed. Both assays detected HIV antibodies in men and women within 2 to 4 weeks of infection, with sensitivity similar to third-generation EIAs.


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Journal of Clinical Microbiology

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February 14, 2012