Academic Commons

Articles

Severity Stages in Essential Tremor: A Long-Term Retrospective Study Using the Glass Scale

Gironell, Alexandre; Ribosa-Nogue, Roser; Gich, Ignasi; Marin-Lahoz, Juan; Pascual-Sedano, Berta

Background: Few prospective studies have attempted to estimate the rate of decline of essential tremor (ET) and these were over a relatively short time period (less than 10 years). We performed a long-term study of severity stages in ET using the Glass Scale scoring system.
Methods: Fifty consecutive patients with severe ET were included. We retrospectively obtained Glass Scale scores throughout the patient’s life. Common milestone events were used to help recall changes in tremor severity.
Results: According to the Glass Scale, the age distributions were as follows: score I, 40 ± 17 years, score II, 55 ± 12 years, score III, 64 ± 9 years, and score IV, 69 ± 7 years. A significant negative correlation between age at first symptom and rate of progression was found (r=-0.669, p < 0.001). The rate of progression was significantly different (p < 0.001) when the first symptom appeared at a younger age (under 40 years of age) compared with older age (40 years or older).
Discussion: Our results support the progressive nature of ET. Age at onset was a prognostic factor. The Glass Scale may be a useful tool to determine severity stages during the course of ET in a manner similar to the Hoehn and Yahr Scale for Parkinson’s disease.

Files

Also Published In

Title
Tremor and Other Hyperkinetic Movements
DOI
https://doi.org/10.7916/D8DV1HQC

More About This Work

Academic Units
Center for Parkinson's Disease and Other Movement Disorders
Published Here
October 14, 2015
Academic Commons provides global access to research and scholarship produced at Columbia University, Barnard College, Teachers College, Union Theological Seminary and Jewish Theological Seminary. Academic Commons is managed by the Columbia University Libraries.