2004 Articles
Visually-guided protein crystal manipulation using micromachined silicon tools
We present a system for protein crystal micro-manipulation with focus on automated crystal mounting for the purposes of X-ray data collection. The system features a set of newly designed micropositioner end-effectors we call microshovels which address some limitations of the traditional cryogenic loops. We have used micro-electrical mechanical system (MEMS) techniques to design and manufacture various shapes and quantities of microshovels. Visual feedback from a camera mounted on the microscope is used to control the micropositioner as it lowers a microshovel into the liquid containing the crystals and approaches a selected crystal for pickup. We present experimental results that illustrate the applicability of our approach.
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Files
- 01389358.pdf application/pdf 503 KB Download File
Also Published In
- Title
- 2004 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS), 28 September - 2 October, 2004, Sendai, Japan: proceedings
- Publisher
- IEEE
- DOI
- https://doi.org/10.1109/IROS.2004.1389358
More About This Work
- Academic Units
- Computer Science
- Published Here
- November 5, 2012