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Concomitant angiosarcoma and lymphoproliferative disorder in solid organ transplant recipients

Baer, Lea; Savage, David G.; Hibshoosh, Hanina; Kalinsky, Kevin

An increased risk of posttransplant malignancy has been consistently reported following various solid organ transplants. The malignancies most commonly encountered are non-melanoma skin cancers, carcinomas of lung or breast and posttransplant lymphoproliferative disorders. Angiosarcoma, an uncommon vascular mesenchymal neoplasm, is rare in the posttransplant setting. This report describes two patients who developed high-grade angiosarcoma following a solid organ transplant. Notably, in both patients, the diagnosis of angiosarcoma was preceded by diagnosis of a lymphoproliferative disorder with monoclonal immunoglobulin heavy chain rearrangement.

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Also Published In

Title
Clinical Sarcoma Research
DOI
https://doi.org/10.1186/2045-3329-4-15

More About This Work

Academic Units
Medicine
Pathology and Cell Biology
Publisher
BioMed Central
Published Here
November 14, 2014