Academic Commons

Articles

fMRI Evidence of Compensatory Mechanisms in Older Adults at Genetic Risk for Alzheimer Disease [Response]

Scarmeas, Nikolaos; Stern, Yaakov

We read the recent article by Bondi et al. with great interest. The authors review previous studies suggesting that blood oxygenation level dependent (BOLD) brain responses during performance of memory tasks are of greater magnitude and more diffuse in patients with early Alzheimer disease (AD) than in normal older individuals. They also review previous studies demonstrating an increase in the intensity and extent of brain activation for non-demented E4 carriers.

Subjects

Files

  • thumnail for Scarmeas-2005-fMRI evidence of compensatory me.pdf Scarmeas-2005-fMRI evidence of compensatory me.pdf application/pdf 117 KB Download File

Also Published In

More About This Work

Academic Units
Neurology
Published Here
June 6, 2018
Academic Commons provides global access to research and scholarship produced at Columbia University, Barnard College, Teachers College, Union Theological Seminary and Jewish Theological Seminary. Academic Commons is managed by the Columbia University Libraries.