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MassTag polymerase chain reaction for differential diagnosis of viral hemorrhagic fevers

Palacios, Gustavo F.; Briese, Thomas; Kapoor, Vishal; Jabado, Omar J.; Liu, Zhiqiang; Venter, Marietjie; Zhai, Junhui; Renwick, Neil; Grolla, Allen; Geisbert, Thomas W.; Drosten, Christian; Towner, Jonathan; Ju, Jingyue; Paweska, Janusz; Nichol, Stuart T.; Swanepoel, Robert; Feldmann, Heinz; Jahrling, Peter B.; Lipkin, W. Ian

Viral hemorrhagic fevers are associated with high rates of illness and death. Although therapeutic options are limited, early differential diagnosis has implications for containment and may aid in clinical management. We describe a diagnostic system for rapid, multiplex polymerase chain reaction identification of 10 different causes of viral hemorrhagic fevers.

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Title
Emerging Infectious Diseases
DOI
https://doi.org/10.3201/eid1204.051515

More About This Work

Academic Units
Center for Infection and Immunity
Published Here
March 17, 2011