ART adherence changes among patients in community substance use treatment: a preliminary analysis from MACH14

Rosen, Marc; Black, Anne; Arnsten, Julia; Simoni, Jane; Wagner, Glann; Goggin, Kathleen; Remien, Robert Howard; Golin, Carol; Wang, Yan; Bangsberg, David; Liu, Honghu

Background: Opiate substitution treatment has been associated with better adherence to lifesaving antiretroviral medications, but the impact of other substance abuse treatment on adherence is unknown. Findings: In this study, 215 patients who had been in adherence-focused research studies provided electronically-measured adherence data and a measure of whether the patient had recently been in substance abuse treatment. Recent engagement in substance abuse treatment was independently associated with significantly higher adherence, after covarying for recent substance use and other factors potentially affecting adherence. Conclusions: The findings suggest that substance abuse treatment is associated with better adherence. Potential mechanisms by which substance abuse treatment improves adherence, such as more stability or more future-orientation, require further study.



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Also Published In

AIDS Research and Therapy

More About This Work

Academic Units
HIV Center for Clinical and Behavioral Studies
BioMed Central
Published Here
September 8, 2014


Medication adherence, AIDS, Substance abuse, Treatment