Academic Commons

Theses Doctoral

Synthetic Studies of the Yunnaneic Acids

Griffith, Daniel

The total syntheses of yunnaneic acid C, yunnaneic acid D, and rufescenolide are described. The highly substituted bicyclic cores of these molecules were synthesized in a single step via a oxidative dearomatization/Diels-Alder cascade sequence from simple precursors. Dimerization studies towards yunnaneic acid A and yunnaneic acid B are also described, which resulted in the synthesis of several novel, non-natural structures.

Subjects

Files

  • thumnail for Griffith_columbia_0054D_11510.pdf Griffith_columbia_0054D_11510.pdf application/x-pdf 12.4 MB Download File

More About This Work

Academic Units
Chemistry
Thesis Advisors
Snyder, Scott A.
Degree
Ph.D., Columbia University
Published Here
August 2, 2013
Academic Commons provides global access to research and scholarship produced at Columbia University, Barnard College, Teachers College, Union Theological Seminary and Jewish Theological Seminary. Academic Commons is managed by the Columbia University Libraries.