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Adrenergic signaling in heart failure and cardiovascular aging

Santulli, Gaetano; Iaccarino, Guido

Both cardiovascular disease and aging are associated with changes in the sympathetic nervous system. Indeed, mounting evidence indicates that adrenergic receptors are functionally involved in numerous processes underlying both aging and cardiovascular disorders, in particular heart failure. This article will review the pathophysiological role of the sympathetic nervous system in heart failure and cardiovascular aging.

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Published In
Maturitas
Publisher DOI
https://doi.org/10.1016/j.maturitas.2016.03.022
Volume
93
Pages
65 - 72
Publisher
Elsevier
Academic Units
Physiology and Cellular Biophysics
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