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Vitamin A Metabolism and Adipose Tissue Biology

Vogel, Silke; Frey, Simone K.

In recent years, the importance of vitamin A in adipose tissue biology, obesity and type II diabetes has become apparent. This review focuses on recent developments within the area of vitamin A and adipose tissue biology. Adipose tissue has an active vitamin A metabolism as it not only stores vitamin A but retinol is also converted to its active metabolite retinoic acid. Several mouse models point to a relationship between vitamin A metabolism and the development of adiposity. Similarly, in vitro studies provide new molecular mechanisms for the function of different forms of vitamin A and retinol- or retinoic acid-binding proteins in adipose tissue.

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Title
Nutrients
DOI
https://doi.org/10.3390/nu3010027

More About This Work

Academic Units
Medicine
Institute of Human Nutrition
Publisher
MDPI Pub.
Published Here
February 27, 2014