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Movements Mimicking Myoclonus Associated with Spinal Cord Pathology: Is This a "Pure Motor Restless Legs Syndrome"?

Ondo, William G.

Background: The neuroanatomic substrate of restless legs syndrome (RLS) is poorly understood, and the diagnosis is clinically made based upon subjective sensory symptoms, although a motor component is usually present. Case Report: We report two cases of elderly patients with spinal pathology who were referred by neurologists for myoclonus. Both had semi-rhythmic leg movements that partially improved while standing, but denied any urge to move. These movements improved dramatically with pramipexole, a dopamine agonist used for RLS. Discussion: We propose that this "myoclonus" is actually the isolated stereotypic motor component of RLS.

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Tremor and Other Hyperkinetic Movements

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Center for Parkinson's Disease and Other Movement Disorders
Published Here
July 5, 2012
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