Movements Mimicking Myoclonus Associated with Spinal Cord Pathology: Is This a "Pure Motor Restless Legs Syndrome"?

Ondo, William G.

Background: The neuroanatomic substrate of restless legs syndrome (RLS) is poorly understood, and the diagnosis is clinically made based upon subjective sensory symptoms, although a motor component is usually present. Case Report: We report two cases of elderly patients with spinal pathology who were referred by neurologists for myoclonus. Both had semi-rhythmic leg movements that partially improved while standing, but denied any urge to move. These movements improved dramatically with pramipexole, a dopamine agonist used for RLS. Discussion: We propose that this "myoclonus" is actually the isolated stereotypic motor component of RLS.



Also Published In

Tremor and Other Hyperkinetic Movements

More About This Work

Academic Units
Center for Parkinson's Disease and Other Movement Disorders
Published Here
July 5, 2012