2014 Articles
CRISPR-mediated genome editing of Plasmodium falciparum malaria parasites
The development of the CRISPR-Cas system is revolutionizing genome editing in a variety of organisms. The system has now been used to manipulate the genome of Plasmodium falciparum, the most lethal malaria-causing species. The ability to generate gene deletions or nucleotide substitutions rapidly and economically promises to accelerate the analysis of novel drug targets and to help elucidate the function of specific genes or gene families, while complementing genome-wide association studies.
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Also Published In
- Title
- Genome Medicine
- DOI
- https://doi.org/10.1186/s13073-014-0063-9
More About This Work
- Academic Units
- Microbiology and Immunology
- Published Here
- September 10, 2015