2005 Articles

Diagnostic system for rapid and sensitive differential detection of pathogens

Briese, Thomas; Palacios, Gustavo F.; Kokoris, Mark; Jabado, Omar J.; Liu, Zhiqiang; Renwick, Neil; Kapoor, Vishal; Casas, Inmaculada; Pozo, Francisco; Limberger, Ron; Perez-Brena, Pilar; Ju, Jingyue; Lipkin, W. Ian

Naturally emerging and deliberately released pathogens demand new detection strategies to allow early recognition and containment. We describe a diagnostic system for rapid, sensitive, multiplex discrimination of microbial gene sequences and report its application for detecting 22 respiratory pathogens in clinical samples.