Articles

Methodological Issues in Clinical Drug Development for Essential Tremor

Carranza, Michael A.; Snyder, Madeline R.; Elble, Rodger J.; Boutzoukas, Angelique E.; Zesiewicz, Theresa A.

Essential tremor (ET) is one of the most common tremor disorders in the world. Despite this, only two medications have received Level A recommendations from the American Academy of Neurology to treat it (primidone and propranolol). Even though these medications provide relief to a large group of ET patients, up to 50% of patients are non-responders. Additional medications to treat ET are needed. This review discusses some of the methodological issues that should be addressed for quality clinical drug development in ET.

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Title
Tremor and Other Hyperkinetic Movements
DOI
https://doi.org/10.5334/tohm.116

More About This Work

Academic Units
Center for Parkinson's Disease and Other Movement Disorders
Published Here
August 21, 2012