1993 Articles
Antecedent clinical features associated with dementia in Parkinson's disease
In a prospective cohort study, we examined clinical features in 250 nondemented patients with idiopathic Parkinson's disease (PD) and then evaluated their association with incident dementia during 5 years of follow-up. Seventy-four of the patients became demented. Odds ratios for incident dementia with PD were increased for the following: being older than 70 years of age (2.7; 1.4 to 5.5), having a PD rating scale score greater than 25 (3.0; 1.5 to 6.2), being depressed (2.7; 1.5 to 6.6), being confused or psychotic on levodopa (3.3; 1.3 to 8.7), or having facial masking as a presenting sign (6.1; 1.4 to 26.9).
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Also Published In
- Title
- Neurology
- DOI
- https://doi.org/10.1212/wnl.43.9.1690
More About This Work
- Academic Units
- Neurology
- Published Here
- February 11, 2022