Real-time monitoring of cardiac radio-frequency ablation lesion formation using an optical coherence tomography forward-imaging catheter

Articles:

Title:: Real-time monitoring of cardiac radio-frequency ablation lesion formation using an optical coherence tomography forward-imaging catheter
Author(s):: Fleming, Christine P.
Wang, Hui
Quan, Kara J.
Rollins, Andrew M.
Date:: 2010
Type:: Articles
Department:: Electrical Engineering
Volume:: 15
Permanent URL:: http://hdl.handle.net/10022/AC:P:15234
Book/Journal Title:: Journal of Biomedical Optics
Abstract:: Radio-frequency ablation (rfa) is the standard of care for the treatment of cardiac arrhythmias; however, there are no direct measures of the successful delivery of ablation lesions. Optical coherence tomography (OCT) imaging has the potential to provide real-time monitoring of cardiac rfa therapy, visualizing lesion formation and assessing tissue contact in the presence of blood. A rfa-compatible forward-imaging conical scanning probe is prototyped to meet this need. The forward-imaging probe provides circular scanning, with a 2-mm scan diameter and 30-μm spot size. During the application of rf energy, dynamics are recorded at 20framespersecond with a 40-kHz A-line rate. Real-time monitoring of cardiac rfa lesion formation and imaging in the presence of blood is demonstrated ex vivo in a swine left ventricle with a forward, flexible, circular scanning OCT catheter.
Subject(s):: Medical imaging and radiology
DOI:: http://dx.doi.org/10.1117/1.3459134