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Visually-guided protein crystal manipulation using micromachined silicon tools

Atanas Georgiev; William Edstrom; Peter K. Allen

Title:
Visually-guided protein crystal manipulation using micromachined silicon tools
Author(s):
Georgiev, Atanas
Edstrom, William
Allen, Peter K.
Date:
Type:
Articles
Department:
Computer Science
Permanent URL:
Book/Journal Title:
2004 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS), 28 September - 2 October, 2004, Sendai, Japan: proceedings
Publisher:
IEEE
Publisher Location:
Piscataway, N.J.
Abstract:
We present a system for protein crystal micro-manipulation with focus on automated crystal mounting for the purposes of X-ray data collection. The system features a set of newly designed micropositioner end-effectors we call microshovels which address some limitations of the traditional cryogenic loops. We have used micro-electrical mechanical system (MEMS) techniques to design and manufacture various shapes and quantities of microshovels. Visual feedback from a camera mounted on the microscope is used to control the micropositioner as it lowers a microshovel into the liquid containing the crystals and approaches a selected crystal for pickup. We present experimental results that illustrate the applicability of our approach.
Subject(s):
Nanotechnology
Publisher DOI:
http://dx.doi.org/10.1109/IROS.2004.1389358
Item views:
126
Metadata:
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