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Cluster analysis of the origins of the new influenza A(H1N1) virus

Alexander V. Solovyov; Gustavo F. Palacios; Thomas Briese; W. Ian Lipkin; Raul Rabadan

Title:
Cluster analysis of the origins of the new influenza A(H1N1) virus
Author(s):
Solovyov, Alexander V.
Palacios, Gustavo F.
Briese, Thomas
Lipkin, W. Ian
Rabadan, Raul
Date:
Type:
Articles
Department:
Center for Infection and Immunity
Volume:
14
Permanent URL:
Book/Journal Title:
Eurosurveillance
Abstract:
In March and April 2009, a new strain of influenza A(H1N1) virus has been isolated in Mexico and the United States. Since the initial reports more than 10,000 cases have been reported to the World Health Organization, all around the world. Several hundred isolates have already been sequenced and deposited in public databases. We have studied the genetics of the new strain and identified its closest relatives through a cluster analysis approach. We show that the new virus combines genetic information related to different swine influenza viruses. Segments PB2, PB1, PA, HA, NP and NS are related to swine H1N2 and H3N2 influenza viruses isolated in North America. Segments NA and M are related to swine influenza viruses isolated in Eurasia.
Subject(s):
Epidemiology
Virology
Item views:
222
Metadata:
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