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Nipah virus outbreak with person-to-person transmission in a district of Bangladesh, 2007

Nusrat Homaira; Mahmudur Rahman; M. Jahangir Hossain; Jonathan H. Epstein; Rebecca Sultana; M. S. U. Khan; Goutam Podder; Kamrun Nahar; Be-Nazir Ahmed; Emily S. Gurley; Peter Daszak; W. Ian Lipkin; Pierre E. Rollin; James A. Comer; Thomas G. Ksiazek; Stephen P. Luby

Title:
Nipah virus outbreak with person-to-person transmission in a district of Bangladesh, 2007
Author(s):
Homaira, Nusrat
Rahman, Mahmudur
Hossain, M. Jahangir
Epstein, Jonathan H.
Sultana, Rebecca
Khan, M. S. U.
Podder, Goutam
Nahar, Kamrun
Ahmed, Be-Nazir
Gurley, Emily S.
Daszak, Peter
Lipkin, W. Ian
Rollin, Pierre E.
Comer, James A.
Ksiazek, Thomas G.
Luby, Stephen P.
Date:
Type:
Articles
Department:
Center for Infection and Immunity
Volume:
138
Permanent URL:
Book/Journal Title:
Epidemiology and infection
Abstract:
In February 2007 an outbreak of Nipah virus (NiV) encephalitis in Thakurgaon District of northwest Bangladesh affected seven people, three of whom died. All subsequent cases developed illness 7-14 days after close physical contact with the index case while he was ill. Cases were more likely than controls to have been in the same room (100% vs. 9.5%, OR undefined, P<0.001). Although the source of infection for the index case was not identified, 50% of Pteropus bats sampled from near the outbreak area 1 month after the outbreak had antibodies to NiV confirming the presence of the virus in the area. The outbreak was spread by person-to-person transmission. Risk of NiV infection in family caregivers highlights the need for infection control practices to limit transmission of potentially infectious body secretions.
Subject(s):
Epidemiology
Immunology
Publisher DOI:
http://dx.doi.org/10.1017/S0950268810000695
Item views:
227
Metadata:
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