Title:

Automatic 4-D Registration in Dynamic MR Renography

Author(s):

Song, Ting
Lee, Vivian S.
Rusinek, Henry
Kaur, Manmeen
Laine, Andrew F.

Date:

2005

Type:

Presentations

Department:

Biomedical Engineering

Permanent URL:

http://hdl.handle.net/10022/AC:P:9509

Notes:

2005 27th Annual International Conference of the IEEE Engineering in Medicine and Biology Society : Shanghai, China, 31 August-03 September 2005 (Piscataway, N.J. : IEEE, 2005), pp. 3067-3070.

Abstract:

Dynamic contrast-enhanced 4-D MR renography has the potential for broad clinical applications, but suffers from respiratory motion that limits analysis and interpretation. Since each examination yields at least over 10 20 serial 3-D images of the abdomen, manual registration is prohibitively labor-intensive. Besides in-plane motion and translation, out-of-plane motion and rotation are observed in the image series. In this paper, a novel robust and automated technique for removing out-of-plane translation and rotation with sub-voxel accuracy in 4-D dynamic MR images is presented. The method was evaluated on simulated motion data derived directly from a clinical patient's data. The method was also tested on 24 clinical patient kidney data sets. Registration results were compared with a mutual information method, in which differences between manually co-registered time-intensity curves and tested time-intensity curves were compared. Evaluation results showed that our method agreed well with these ground truth data.

Subject(s):

Biomedical engineering

DOI:

http://dx.doi.org/10.1109/IEMBS.2005.1617122

Item views:

164

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