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LV Volume Quantification via Spatiotemporal Analysis of Real-Time 3-D Echocardiography

Elsa D. Angelini; Andrew F. Laine; Shin Takuma; Jeffrey W. Holmes; Shunichi Homma

Title:
LV Volume Quantification via Spatiotemporal Analysis of Real-Time 3-D Echocardiography
Author(s):
Angelini, Elsa D.
Laine, Andrew F.
Takuma, Shin
Holmes, Jeffrey W.
Homma, Shunichi
Date:
Type:
Articles
Department:
Biomedical Engineering
Volume:
20
Permanent URL:
Book/Journal Title:
IEEE Transactions on Medical Imaging
Abstract:
This paper presents a method of four-dimensional (4-D) (3-D+Time) space-frequency analysis for directional denoising and enhancement of real-time three-dimensional (RT3D) ultrasound and quantitative measures in diagnostic cardiac ultrasound. Expansion of echocardiographic volumes is performed with complex exponential wavelet-like basis functions called brushlets. These functions offer good localization in time and frequency and decompose a signal into distinct patterns of oriented harmonics, which are invariant to intensity and contrast range. Deformable-model segmentation is carried out on denoised data after thresholding of transform coefficients. This process attenuates speckle noise while preserving cardiac structure location. The superiority of 4-D over 3-D analysis for decorrelating additive white noise and multiplicative speckle noise on a 4-D phantom volume expanding in time is demonstrated. Quantitative validation, computed for contours and volumes, is performed on in vitro balloon phantoms. Clinical applications of this spatiotemporal analysis tool are reported for six patient cases providing measures of left ventricular volumes and ejection fraction.
Subject(s):
Biomedical engineering
Publisher DOI:
http://dx.doi.org/10.1109/42.929612
Item views:
112
Metadata:
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