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Automated streak-seeding with micromachined silicon tools

Atanas Georgiev; Sergeui M. Vorobiev; William Edstrom; Ting Song; Andrew F. Laine; John F. Hunt; Peter K. Allen

Title:
Automated streak-seeding with micromachined silicon tools
Author(s):
Georgiev, Atanas
Vorobiev, Sergeui M.
Edstrom, William
Song, Ting
Laine, Andrew F.
Hunt, John F.
Allen, Peter K.
Date:
Type:
Articles
Department:
Biomedical Engineering
Volume:
D62
Permanent URL:
Book/Journal Title:
Acta Crystallographica Section D
Abstract:
This report presents a new approach to streak-seeding based on custom-designed silicon microtools. Experimental data show that the microtools produce similar results to the commonly used boar bristles. One advantage to using silicon is that it is rigid and can easily serve as an accurately calibrated end-effector on a micro-robotic system. Additionally, the fabrication technology allows the production of microtools of various shapes and sizes. A working prototype of an automatic streak-seeding system based on these microtools was built and successfully applied for protein crystallization.
Subject(s):
Biomedical engineering
Publisher DOI:
http://dx.doi.org/10.1107/S0907444906023705
Item views:
196
Metadata:
text | xml

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