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Cardiovascular Changes in Cardiogenic and Obstructive Shocks: Analysis Using a Cardiopulmonary Simulation Model

Massimo Giannessi; Nicolas W. Chbat; Antonio Albanese; J. Op Den Buijs; E. Magosso; Mauro Ursino

Title:
Cardiovascular Changes in Cardiogenic and Obstructive Shocks: Analysis Using a Cardiopulmonary Simulation Model
Author(s):
Giannessi, Massimo
Chbat, Nicolas W.
Albanese, Antonio
Buijs, J. Op Den
Magosso, E.
Ursino, Mauro
Date:
Type:
Articles
Department:
Biomedical Engineering
Permanent URL:
Book/Journal Title:
Computers in Cardiology 2008: Volume 35: September 14-17, 2008, Bologna, Italy
Publisher:
IEEE
Publisher Location:
Piscataway, N.J.
Abstract:
Conditions characterized by a fall in cardiac output are associated with alterations in cardiopulmonary variables and activation of cardiovascular and respiratory control mechanisms. In order to study these complex relationships, we developed a comprehensive cardiopulmonary model consisting of a circulation, a respiration and a metabolism block. In this work, the model is used to simulate cardiovascular dynamics in pathological conditions with an acute decrease in heart function. In particular, two conditions are examined: the first is characterized by a decrease in heart contractility, simulated in the model via a reduction in the left ventricular end-systolic elastance. The second consists in an increase in pulmonary arterial resistance, associated with pulmonary embolism. In conclusion, the proposed model may be of value in clinical settings to illustrate the complex relationship among cardiovascular variables.
Subject(s):
Biomedical engineering
Publisher DOI:
http://dx.doi.org/10.1109/CIC.2008.4749077
Item views:
132
Metadata:
text | xml

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