Title:

Streak Seeding Automation Using Silicon Tools

Author(s):

Georgiev, Atanas
Vorobiev, Sergeui M.
Edstrom, William
Song, Ting
Laine, Andrew F.
Hunt, John F.
Allen, Peter K.

Date:

2006

Type:

Technical reports

Department:

Computer Science

Permanent URL:

http://hdl.handle.net/10022/AC:P:29452

Series:

Columbia University Computer Science Technical Reports

Part Number:

CUCS-015-06

Publisher:

Department of Computer Science, Columbia University

Publisher Location:

New York

Abstract:

This report presents an approach to automation of a protein crystallography task called streak seeding. The approach is based on novel and unique custom-designed silicon microtools, which we experimentally verified to produce results similar to the results from traditionally used boar bristles. The advantage to using silicon is that it allows the employment of state-of-the-art micro-electro-mechanical-systems (MEMS) technology to produce microtools of various shapes and sizes and that it is rigid and can be easily adopted as an accurately calibrated end-effector on a microrobotic system. A working prototype of an automatic streak seeding system is presented, which has been successfully applied for protein crystallization.

Subject(s):

Computer science

Item views:

232

Metadata:

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