Technical reports:
A Microrobotic System For Protein Streak Seeding
Atanas Georgiev; Peter K. Allen; Ting Song; Andrew F. Laine; William Edstrom; John F. Hunt
Downloads:
- Title:
- A Microrobotic System For Protein Streak Seeding
- Author(s):
-
Georgiev, Atanas
Allen, Peter K.
Song, Ting
Laine, Andrew F.
Edstrom, William
Hunt, John F. - Date:
- 2004
- Type:
- Technical reports
- Department:
- Computer Science
- Permanent URL:
- http://hdl.handle.net/10022/AC:P:29243
- Series:
- Columbia University Computer Science Technical Reports
- Part Number:
- CUCS-041-04
- Publisher:
- Department of Computer Science, Columbia University
- Publisher Location:
- New York
- Abstract:
- We present a microrobotic system for protein crystal micromanipulation tasks. The focus in this report is on a task called streak seeding, which is used by crystallographers to entice certain protein crystals to grow. Our system features a set of custom designed micropositioner end-effectors we call microshovels to replace traditional tools used by crystallographers for this task. We have used micro-electrical mechanical system (MEMS) techniques to design and manufacture various shapes and quantities of microshovels. Visual feedback from a camera mounted on the microscope is used to control the micropositioner as it lowers a microshovel into the liquid containing the crystals for poking and streaking. We present experimental results that illustrate the applicability of our approach.
- Subject(s):
- Computer science
- Item views:
- 48