A Microrobotic System For Protein Streak Seeding
Atanas Georgiev; Peter K. Allen; Ting Song; Andrew F. Laine; William Edstrom; John F. Hunt
- A Microrobotic System For Protein Streak Seeding
Allen, Peter K.
Laine, Andrew F.
Hunt, John F.
- Technical reports
- Computer Science
- Permanent URL:
- Columbia University Computer Science Technical Reports
- Part Number:
- Department of Computer Science, Columbia University
- Publisher Location:
- New York
- We present a microrobotic system for protein crystal micromanipulation tasks. The focus in this report is on a task called streak seeding, which is used by crystallographers to entice certain protein crystals to grow. Our system features a set of custom designed micropositioner end-effectors we call microshovels to replace traditional tools used by crystallographers for this task. We have used micro-electrical mechanical system (MEMS) techniques to design and manufacture various shapes and quantities of microshovels. Visual feedback from a camera mounted on the microscope is used to control the micropositioner as it lowers a microshovel into the liquid containing the crystals for poking and streaking. We present experimental results that illustrate the applicability of our approach.
- Computer science
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